Amniotic membrane: from structure and functions to clinical applications
Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the plu...
Gespeichert in:
| Veröffentlicht in: | Cell and tissue research 2012-08, Vol.349 (2), p.447-458 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 458 |
|---|---|
| container_issue | 2 |
| container_start_page | 447 |
| container_title | Cell and tissue research |
| container_volume | 349 |
| creator | Mamede, A. C Carvalho, M. J Abrantes, A. M Laranjo, M Maia, C. J Botelho, M. F |
| description | Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the pluripotent properties of AM cells, which are an attractive source for tissue transplantation. AM has anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics, as well as anti-angiogenic and pro-apoptotic features. AM is a promoter of epithelialization and is a non-tumorigenic tissue and its use has no ethical problems. Because of its attractive properties, AM has been applied in several surgical procedures related to ocular surface reconstruction and the genito-urinary tract, skin, head and neck, among others. So far, the best known and most auspicious applications of AM are ocular surface reconstruction, skin applications and tissue engineering. However, AM can also be applied in oncology. In this area, AM can prevent the delivery of nutrients and oxygen to cancer cells and consequently interfere with tumour angiogenesis, growth and metastasis. |
| doi_str_mv | 10.1007/s00441-012-1424-6 |
| format | Article |
| fullrecord | <record><control><sourceid>gale_proqu</sourceid><recordid>TN_cdi_proquest_miscellaneous_1033157649</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><galeid>A373253941</galeid><sourcerecordid>A373253941</sourcerecordid><originalsourceid>FETCH-LOGICAL-c587t-9d1052f9c6be37b71f7db4eadbff9a94d49468015b3bb5e5f9a467f5393ad9243</originalsourceid><addsrcrecordid>eNp1kk1vFSEUhonR2NvqD3CjkzQxbqbyNTC4u2msNWnShTZxR4CBW5oZuAKz8N-X6VRtjQ0LyDnPeziHFwDeIHiCIOQfM4SUohYi3CKKacuegQ2iBLew5_1zsIEE4pYz9uMAHOZ8AyGijImX4ADjTmCG6Qacb6fgY_Gmmeykkwr2U-NSnJpc0mzKnGyjwtC4OZjiY8hNiY0ZffBGjY3a78d6uEu8Ai-cGrN9fb8fgauzz99Pz9uLyy9fT7cXrel6XloxINhhJwzTlnDNkeODplYN2jmhBB2ooKyHqNNE6852NUgZdx0RRA0CU3IEPqx19yn-nG0ucvLZ2HGsrcc5SwQJQR1nVFT0-B_0Js4p1O4WCnPeiR79pXZqtNIHF0tSZikqt4QTXK-mC3XyH6quwU7exGCdr_FHgvcPBNdWjeU6x3G-e6zHIFpBk2LOyTq5T35S6VdtUi42y9VmWW2Wi82SVc3b-8lmPdnhj-K3rxXAK5BrKuxsejj601XfrSKnolS75LO8-obrp6kfh1DECbkF5bi4mw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1032775981</pqid></control><display><type>article</type><title>Amniotic membrane: from structure and functions to clinical applications</title><source>MEDLINE</source><source>SpringerLink Journals</source><creator>Mamede, A. C ; Carvalho, M. J ; Abrantes, A. M ; Laranjo, M ; Maia, C. J ; Botelho, M. F</creator><creatorcontrib>Mamede, A. C ; Carvalho, M. J ; Abrantes, A. M ; Laranjo, M ; Maia, C. J ; Botelho, M. F</creatorcontrib><description>Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the pluripotent properties of AM cells, which are an attractive source for tissue transplantation. AM has anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics, as well as anti-angiogenic and pro-apoptotic features. AM is a promoter of epithelialization and is a non-tumorigenic tissue and its use has no ethical problems. Because of its attractive properties, AM has been applied in several surgical procedures related to ocular surface reconstruction and the genito-urinary tract, skin, head and neck, among others. So far, the best known and most auspicious applications of AM are ocular surface reconstruction, skin applications and tissue engineering. However, AM can also be applied in oncology. In this area, AM can prevent the delivery of nutrients and oxygen to cancer cells and consequently interfere with tumour angiogenesis, growth and metastasis.</description><identifier>ISSN: 0302-766X</identifier><identifier>EISSN: 1432-0878</identifier><identifier>DOI: 10.1007/s00441-012-1424-6</identifier><identifier>PMID: 22592624</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>amnion ; Amnion - cytology ; Amnion - immunology ; Amnion - transplantation ; angiogenesis ; Animals ; Antiviral agents ; Biomedical and Life Sciences ; Biomedicine ; ethics ; head ; Human Genetics ; Humans ; Membranes ; Metastasis ; Molecular Medicine ; neck ; nutrients ; Oncology ; Ophthalmologic Surgical Procedures - methods ; oxygen ; placenta ; Proteomics ; Reconstructive Surgical Procedures - methods ; Regenerative Medicine - methods ; Review ; Skin ; Tissue engineering ; Tissue Engineering - methods ; tissue transplantation ; Tumors</subject><ispartof>Cell and tissue research, 2012-08, Vol.349 (2), p.447-458</ispartof><rights>Springer-Verlag 2012</rights><rights>COPYRIGHT 2012 Springer</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c587t-9d1052f9c6be37b71f7db4eadbff9a94d49468015b3bb5e5f9a467f5393ad9243</citedby><cites>FETCH-LOGICAL-c587t-9d1052f9c6be37b71f7db4eadbff9a94d49468015b3bb5e5f9a467f5393ad9243</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s00441-012-1424-6$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s00441-012-1424-6$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22592624$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mamede, A. C</creatorcontrib><creatorcontrib>Carvalho, M. J</creatorcontrib><creatorcontrib>Abrantes, A. M</creatorcontrib><creatorcontrib>Laranjo, M</creatorcontrib><creatorcontrib>Maia, C. J</creatorcontrib><creatorcontrib>Botelho, M. F</creatorcontrib><title>Amniotic membrane: from structure and functions to clinical applications</title><title>Cell and tissue research</title><addtitle>Cell Tissue Res</addtitle><addtitle>Cell Tissue Res</addtitle><description>Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the pluripotent properties of AM cells, which are an attractive source for tissue transplantation. AM has anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics, as well as anti-angiogenic and pro-apoptotic features. AM is a promoter of epithelialization and is a non-tumorigenic tissue and its use has no ethical problems. Because of its attractive properties, AM has been applied in several surgical procedures related to ocular surface reconstruction and the genito-urinary tract, skin, head and neck, among others. So far, the best known and most auspicious applications of AM are ocular surface reconstruction, skin applications and tissue engineering. However, AM can also be applied in oncology. In this area, AM can prevent the delivery of nutrients and oxygen to cancer cells and consequently interfere with tumour angiogenesis, growth and metastasis.</description><subject>amnion</subject><subject>Amnion - cytology</subject><subject>Amnion - immunology</subject><subject>Amnion - transplantation</subject><subject>angiogenesis</subject><subject>Animals</subject><subject>Antiviral agents</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>ethics</subject><subject>head</subject><subject>Human Genetics</subject><subject>Humans</subject><subject>Membranes</subject><subject>Metastasis</subject><subject>Molecular Medicine</subject><subject>neck</subject><subject>nutrients</subject><subject>Oncology</subject><subject>Ophthalmologic Surgical Procedures - methods</subject><subject>oxygen</subject><subject>placenta</subject><subject>Proteomics</subject><subject>Reconstructive Surgical Procedures - methods</subject><subject>Regenerative Medicine - methods</subject><subject>Review</subject><subject>Skin</subject><subject>Tissue engineering</subject><subject>Tissue Engineering - methods</subject><subject>tissue transplantation</subject><subject>Tumors</subject><issn>0302-766X</issn><issn>1432-0878</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp1kk1vFSEUhonR2NvqD3CjkzQxbqbyNTC4u2msNWnShTZxR4CBW5oZuAKz8N-X6VRtjQ0LyDnPeziHFwDeIHiCIOQfM4SUohYi3CKKacuegQ2iBLew5_1zsIEE4pYz9uMAHOZ8AyGijImX4ADjTmCG6Qacb6fgY_Gmmeykkwr2U-NSnJpc0mzKnGyjwtC4OZjiY8hNiY0ZffBGjY3a78d6uEu8Ai-cGrN9fb8fgauzz99Pz9uLyy9fT7cXrel6XloxINhhJwzTlnDNkeODplYN2jmhBB2ooKyHqNNE6852NUgZdx0RRA0CU3IEPqx19yn-nG0ucvLZ2HGsrcc5SwQJQR1nVFT0-B_0Js4p1O4WCnPeiR79pXZqtNIHF0tSZikqt4QTXK-mC3XyH6quwU7exGCdr_FHgvcPBNdWjeU6x3G-e6zHIFpBk2LOyTq5T35S6VdtUi42y9VmWW2Wi82SVc3b-8lmPdnhj-K3rxXAK5BrKuxsejj601XfrSKnolS75LO8-obrp6kfh1DECbkF5bi4mw</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Mamede, A. C</creator><creator>Carvalho, M. J</creator><creator>Abrantes, A. M</creator><creator>Laranjo, M</creator><creator>Maia, C. J</creator><creator>Botelho, M. F</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>FBQ</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7RV</scope><scope>7SS</scope><scope>7TK</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>RC3</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>Amniotic membrane: from structure and functions to clinical applications</title><author>Mamede, A. C ; Carvalho, M. J ; Abrantes, A. M ; Laranjo, M ; Maia, C. J ; Botelho, M. F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c587t-9d1052f9c6be37b71f7db4eadbff9a94d49468015b3bb5e5f9a467f5393ad9243</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>amnion</topic><topic>Amnion - cytology</topic><topic>Amnion - immunology</topic><topic>Amnion - transplantation</topic><topic>angiogenesis</topic><topic>Animals</topic><topic>Antiviral agents</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>ethics</topic><topic>head</topic><topic>Human Genetics</topic><topic>Humans</topic><topic>Membranes</topic><topic>Metastasis</topic><topic>Molecular Medicine</topic><topic>neck</topic><topic>nutrients</topic><topic>Oncology</topic><topic>Ophthalmologic Surgical Procedures - methods</topic><topic>oxygen</topic><topic>placenta</topic><topic>Proteomics</topic><topic>Reconstructive Surgical Procedures - methods</topic><topic>Regenerative Medicine - methods</topic><topic>Review</topic><topic>Skin</topic><topic>Tissue engineering</topic><topic>Tissue Engineering - methods</topic><topic>tissue transplantation</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mamede, A. C</creatorcontrib><creatorcontrib>Carvalho, M. J</creatorcontrib><creatorcontrib>Abrantes, A. M</creatorcontrib><creatorcontrib>Laranjo, M</creatorcontrib><creatorcontrib>Maia, C. J</creatorcontrib><creatorcontrib>Botelho, M. F</creatorcontrib><collection>AGRIS</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Nursing & Allied Health Database</collection><collection>Entomology Abstracts (Full archive)</collection><collection>Neurosciences Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Biological Science Database</collection><collection>Nursing & Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Cell and tissue research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mamede, A. C</au><au>Carvalho, M. J</au><au>Abrantes, A. M</au><au>Laranjo, M</au><au>Maia, C. J</au><au>Botelho, M. F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Amniotic membrane: from structure and functions to clinical applications</atitle><jtitle>Cell and tissue research</jtitle><stitle>Cell Tissue Res</stitle><addtitle>Cell Tissue Res</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>349</volume><issue>2</issue><spage>447</spage><epage>458</epage><pages>447-458</pages><issn>0302-766X</issn><eissn>1432-0878</eissn><abstract>Amniotic membrane (AM) or amnion is a thin membrane on the inner side of the fetal placenta; it completely surrounds the embryo and delimits the amniotic cavity, which is filled by amniotic liquid. In recent years, the structure and function of the amnion have been investigated, particularly the pluripotent properties of AM cells, which are an attractive source for tissue transplantation. AM has anti-inflammatory, anti-bacterial, anti-viral and immunological characteristics, as well as anti-angiogenic and pro-apoptotic features. AM is a promoter of epithelialization and is a non-tumorigenic tissue and its use has no ethical problems. Because of its attractive properties, AM has been applied in several surgical procedures related to ocular surface reconstruction and the genito-urinary tract, skin, head and neck, among others. So far, the best known and most auspicious applications of AM are ocular surface reconstruction, skin applications and tissue engineering. However, AM can also be applied in oncology. In this area, AM can prevent the delivery of nutrients and oxygen to cancer cells and consequently interfere with tumour angiogenesis, growth and metastasis.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>22592624</pmid><doi>10.1007/s00441-012-1424-6</doi><tpages>12</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0302-766X |
| ispartof | Cell and tissue research, 2012-08, Vol.349 (2), p.447-458 |
| issn | 0302-766X 1432-0878 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1033157649 |
| source | MEDLINE; SpringerLink Journals |
| subjects | amnion Amnion - cytology Amnion - immunology Amnion - transplantation angiogenesis Animals Antiviral agents Biomedical and Life Sciences Biomedicine ethics head Human Genetics Humans Membranes Metastasis Molecular Medicine neck nutrients Oncology Ophthalmologic Surgical Procedures - methods oxygen placenta Proteomics Reconstructive Surgical Procedures - methods Regenerative Medicine - methods Review Skin Tissue engineering Tissue Engineering - methods tissue transplantation Tumors |
| title | Amniotic membrane: from structure and functions to clinical applications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-14T06%3A07%3A43IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-gale_proqu&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Amniotic%20membrane:%20from%20structure%20and%20functions%20to%20clinical%20applications&rft.jtitle=Cell%20and%20tissue%20research&rft.au=Mamede,%20A.%20C&rft.date=2012-08-01&rft.volume=349&rft.issue=2&rft.spage=447&rft.epage=458&rft.pages=447-458&rft.issn=0302-766X&rft.eissn=1432-0878&rft_id=info:doi/10.1007/s00441-012-1424-6&rft_dat=%3Cgale_proqu%3EA373253941%3C/gale_proqu%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1032775981&rft_id=info:pmid/22592624&rft_galeid=A373253941&rfr_iscdi=true |