A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer's disease
Objective: To analyze the influence of a six-month exercise program on neuropsychiatric disorders and on the performance of instrumental activities in elderly patients with Alzheimer's disease (AD). Methods: The study included 20 patients with AD in the mild to moderate stages of the Clinical D...
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Veröffentlicht in: | Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil)) Brazil)), 2012-06, Vol.16 (3), p.197-204 |
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description | Objective: To analyze the influence of a six-month exercise program on neuropsychiatric disorders and on the performance of instrumental activities in elderly patients with Alzheimer's disease (AD). Methods: The study included 20 patients with AD in the mild to moderate stages of the Clinical Dementia Rating (CDR) divided into two groups: the experimental group, composed of 10 women who participated in the six-month exercise program, and the control group, composed of the 10 remaining AD patients who did not take part in an exercise program during the same period. All participants were evaluated using the Mini-Mental State Exam for global cognitive function, the Neuropsychiatric Inventory Questionnaire for neuropsychiatric disorders, and the Pfeffer Functional Activities Questionnaire for the degree of functional impairment. Results: The control group showed functional and neuropsychiatric deterioration in the comparisons between pre- and post-intervention times and between groups. Conclusion: The experimental group showed a propensity for less deterioration in neuropsychiatric disorders and performance of instrumental activities compared to the sedentary group.Original Abstract: Objetivo: Analisar os efeitos de seis meses de intervencao de um programa de atividade fisica sobre os disturbios neuropsiquiatricos e o desempenho nas atividades instrumentais da vida diaria de idosos com Doenca de Alzheimer (DA). Metodos: Foram recrutados 20 pacientes nos estagios entre leve e moderado da DA. Segundo o escore clinico de demencia (CDR), foram distribuidos em dois grupos: o grupo treinamento (GT), composto por dez mulheres que participaram de um program de exercfcios fisicos por um periodo de seis meses, e o grupo controle (GC), composto por dez outras participantes que nao realizaram nenhum tipo de intervencao motora estruturada durante o mesmo periodo. Todas as participantes foram avaliadas por meio do Miniexame do Estado Mental, para obtencao da caracterizacao cognitiva; Inventario Neuropsiquiatrico, para identificacao dos disturbios neuropsiquiatricos mais prevalentes e Questionario de Atividades Instrumentais de Pfeffer, para verificacao do grau de comprometimento funcional. Resultados: Os participantes do GC mostraram uma deterioracao tanto no desempenho das atividades instrumentais quanta na intensificacao dos disturbios neuropsiquiatricos, quando comparados os momentos pre e pos-intervencao. Conclusao: O GT demonstrou uma atenuacao da intensificacao dos di |
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Methods: The study included 20 patients with AD in the mild to moderate stages of the Clinical Dementia Rating (CDR) divided into two groups: the experimental group, composed of 10 women who participated in the six-month exercise program, and the control group, composed of the 10 remaining AD patients who did not take part in an exercise program during the same period. All participants were evaluated using the Mini-Mental State Exam for global cognitive function, the Neuropsychiatric Inventory Questionnaire for neuropsychiatric disorders, and the Pfeffer Functional Activities Questionnaire for the degree of functional impairment. Results: The control group showed functional and neuropsychiatric deterioration in the comparisons between pre- and post-intervention times and between groups. Conclusion: The experimental group showed a propensity for less deterioration in neuropsychiatric disorders and performance of instrumental activities compared to the sedentary group.Original Abstract: Objetivo: Analisar os efeitos de seis meses de intervencao de um programa de atividade fisica sobre os disturbios neuropsiquiatricos e o desempenho nas atividades instrumentais da vida diaria de idosos com Doenca de Alzheimer (DA). Metodos: Foram recrutados 20 pacientes nos estagios entre leve e moderado da DA. Segundo o escore clinico de demencia (CDR), foram distribuidos em dois grupos: o grupo treinamento (GT), composto por dez mulheres que participaram de um program de exercfcios fisicos por um periodo de seis meses, e o grupo controle (GC), composto por dez outras participantes que nao realizaram nenhum tipo de intervencao motora estruturada durante o mesmo periodo. Todas as participantes foram avaliadas por meio do Miniexame do Estado Mental, para obtencao da caracterizacao cognitiva; Inventario Neuropsiquiatrico, para identificacao dos disturbios neuropsiquiatricos mais prevalentes e Questionario de Atividades Instrumentais de Pfeffer, para verificacao do grau de comprometimento funcional. Resultados: Os participantes do GC mostraram uma deterioracao tanto no desempenho das atividades instrumentais quanta na intensificacao dos disturbios neuropsiquiatricos, quando comparados os momentos pre e pos-intervencao. Conclusao: O GT demonstrou uma atenuacao da intensificacao dos disturbios neuropsiquiatricos e do desempenho funcional em relacao ao grupo sedentario.</description><identifier>ISSN: 1413-3555</identifier><language>por</language><subject>Activities ; Alzheimer's disease ; Clinical trials ; Cognitive ability ; Dementia disorders ; Exercise (programs) ; Geriatrics ; Inventories ; Mental disorders ; Neurodegenerative diseases ; Objectives ; Patients ; Physical training ; Surveys ; Women</subject><ispartof>Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil)), 2012-06, Vol.16 (3), p.197-204</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,778,782</link.rule.ids></links><search><creatorcontrib>Nascimento, CMC</creatorcontrib><creatorcontrib>Teixeira, CVL</creatorcontrib><creatorcontrib>Gobbi, LTB</creatorcontrib><creatorcontrib>Gobbi, S</creatorcontrib><creatorcontrib>Stella, F</creatorcontrib><title>A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer's disease</title><title>Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil))</title><description>Objective: To analyze the influence of a six-month exercise program on neuropsychiatric disorders and on the performance of instrumental activities in elderly patients with Alzheimer's disease (AD). Methods: The study included 20 patients with AD in the mild to moderate stages of the Clinical Dementia Rating (CDR) divided into two groups: the experimental group, composed of 10 women who participated in the six-month exercise program, and the control group, composed of the 10 remaining AD patients who did not take part in an exercise program during the same period. All participants were evaluated using the Mini-Mental State Exam for global cognitive function, the Neuropsychiatric Inventory Questionnaire for neuropsychiatric disorders, and the Pfeffer Functional Activities Questionnaire for the degree of functional impairment. Results: The control group showed functional and neuropsychiatric deterioration in the comparisons between pre- and post-intervention times and between groups. Conclusion: The experimental group showed a propensity for less deterioration in neuropsychiatric disorders and performance of instrumental activities compared to the sedentary group.Original Abstract: Objetivo: Analisar os efeitos de seis meses de intervencao de um programa de atividade fisica sobre os disturbios neuropsiquiatricos e o desempenho nas atividades instrumentais da vida diaria de idosos com Doenca de Alzheimer (DA). Metodos: Foram recrutados 20 pacientes nos estagios entre leve e moderado da DA. Segundo o escore clinico de demencia (CDR), foram distribuidos em dois grupos: o grupo treinamento (GT), composto por dez mulheres que participaram de um program de exercfcios fisicos por um periodo de seis meses, e o grupo controle (GC), composto por dez outras participantes que nao realizaram nenhum tipo de intervencao motora estruturada durante o mesmo periodo. Todas as participantes foram avaliadas por meio do Miniexame do Estado Mental, para obtencao da caracterizacao cognitiva; Inventario Neuropsiquiatrico, para identificacao dos disturbios neuropsiquiatricos mais prevalentes e Questionario de Atividades Instrumentais de Pfeffer, para verificacao do grau de comprometimento funcional. Resultados: Os participantes do GC mostraram uma deterioracao tanto no desempenho das atividades instrumentais quanta na intensificacao dos disturbios neuropsiquiatricos, quando comparados os momentos pre e pos-intervencao. Conclusao: O GT demonstrou uma atenuacao da intensificacao dos disturbios neuropsiquiatricos e do desempenho funcional em relacao ao grupo sedentario.</description><subject>Activities</subject><subject>Alzheimer's disease</subject><subject>Clinical trials</subject><subject>Cognitive ability</subject><subject>Dementia disorders</subject><subject>Exercise (programs)</subject><subject>Geriatrics</subject><subject>Inventories</subject><subject>Mental disorders</subject><subject>Neurodegenerative diseases</subject><subject>Objectives</subject><subject>Patients</subject><subject>Physical training</subject><subject>Surveys</subject><subject>Women</subject><issn>1413-3555</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNqVjEFOwzAURL0oEoVyh7-DTSUnwVVZVgjEAdhXljNRPnLs1v-nBY7BiXElLsBmRpp5MwuzbB6bbt05567NjciHtW7btHZpfnYUctKSY0RPIXLi4CNp4ao5kY4gDAOCCuWB8IkSWHCpEuaSD_IVRvaVD9Sz5NKjCPnUEyfRMk9IWp98UD6xMqTmdM41pjPrSLv4PYInlHu57OEFK3M1-Ci4-_Nb8_D68v78tj6UfJwhup9YAmL0CXmWfWO7dvu0sa3r_oH-AkkJXA0</recordid><startdate>20120601</startdate><enddate>20120601</enddate><creator>Nascimento, CMC</creator><creator>Teixeira, CVL</creator><creator>Gobbi, LTB</creator><creator>Gobbi, S</creator><creator>Stella, F</creator><scope>7TK</scope><scope>7TS</scope></search><sort><creationdate>20120601</creationdate><title>A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer's disease</title><author>Nascimento, CMC ; Teixeira, CVL ; Gobbi, LTB ; Gobbi, S ; Stella, F</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_10328960253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>por</language><creationdate>2012</creationdate><topic>Activities</topic><topic>Alzheimer's disease</topic><topic>Clinical trials</topic><topic>Cognitive ability</topic><topic>Dementia disorders</topic><topic>Exercise (programs)</topic><topic>Geriatrics</topic><topic>Inventories</topic><topic>Mental disorders</topic><topic>Neurodegenerative diseases</topic><topic>Objectives</topic><topic>Patients</topic><topic>Physical training</topic><topic>Surveys</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nascimento, CMC</creatorcontrib><creatorcontrib>Teixeira, CVL</creatorcontrib><creatorcontrib>Gobbi, LTB</creatorcontrib><creatorcontrib>Gobbi, S</creatorcontrib><creatorcontrib>Stella, F</creatorcontrib><collection>Neurosciences Abstracts</collection><collection>Physical Education Index</collection><jtitle>Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil))</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nascimento, CMC</au><au>Teixeira, CVL</au><au>Gobbi, LTB</au><au>Gobbi, S</au><au>Stella, F</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer's disease</atitle><jtitle>Revista brasileira de fisioterapia (São Carlos (São Paulo, Brazil))</jtitle><date>2012-06-01</date><risdate>2012</risdate><volume>16</volume><issue>3</issue><spage>197</spage><epage>204</epage><pages>197-204</pages><issn>1413-3555</issn><abstract>Objective: To analyze the influence of a six-month exercise program on neuropsychiatric disorders and on the performance of instrumental activities in elderly patients with Alzheimer's disease (AD). Methods: The study included 20 patients with AD in the mild to moderate stages of the Clinical Dementia Rating (CDR) divided into two groups: the experimental group, composed of 10 women who participated in the six-month exercise program, and the control group, composed of the 10 remaining AD patients who did not take part in an exercise program during the same period. All participants were evaluated using the Mini-Mental State Exam for global cognitive function, the Neuropsychiatric Inventory Questionnaire for neuropsychiatric disorders, and the Pfeffer Functional Activities Questionnaire for the degree of functional impairment. Results: The control group showed functional and neuropsychiatric deterioration in the comparisons between pre- and post-intervention times and between groups. Conclusion: The experimental group showed a propensity for less deterioration in neuropsychiatric disorders and performance of instrumental activities compared to the sedentary group.Original Abstract: Objetivo: Analisar os efeitos de seis meses de intervencao de um programa de atividade fisica sobre os disturbios neuropsiquiatricos e o desempenho nas atividades instrumentais da vida diaria de idosos com Doenca de Alzheimer (DA). Metodos: Foram recrutados 20 pacientes nos estagios entre leve e moderado da DA. Segundo o escore clinico de demencia (CDR), foram distribuidos em dois grupos: o grupo treinamento (GT), composto por dez mulheres que participaram de um program de exercfcios fisicos por um periodo de seis meses, e o grupo controle (GC), composto por dez outras participantes que nao realizaram nenhum tipo de intervencao motora estruturada durante o mesmo periodo. Todas as participantes foram avaliadas por meio do Miniexame do Estado Mental, para obtencao da caracterizacao cognitiva; Inventario Neuropsiquiatrico, para identificacao dos disturbios neuropsiquiatricos mais prevalentes e Questionario de Atividades Instrumentais de Pfeffer, para verificacao do grau de comprometimento funcional. Resultados: Os participantes do GC mostraram uma deterioracao tanto no desempenho das atividades instrumentais quanta na intensificacao dos disturbios neuropsiquiatricos, quando comparados os momentos pre e pos-intervencao. Conclusao: O GT demonstrou uma atenuacao da intensificacao dos disturbios neuropsiquiatricos e do desempenho funcional em relacao ao grupo sedentario.</abstract></addata></record> |
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subjects | Activities Alzheimer's disease Clinical trials Cognitive ability Dementia disorders Exercise (programs) Geriatrics Inventories Mental disorders Neurodegenerative diseases Objectives Patients Physical training Surveys Women |
title | A controlled clinical trial on the effects of exercise on neuropsychiatric disorders and instrumental activities in women with Alzheimer's disease |
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