Claudin-4 Expression Predicts Survival in Pancreatic Ductal Adenocarcinoma

Background Identification of prognostic markers would be useful in the clinical management of patients with pancreatic ductal adenocarcinoma (PDAC). The clinical relevance of claudin-4 (CLDN4), recently identified as overexpressed in PDAC, is unknown. Methods Using quantitative real-time reverse tra...

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Veröffentlicht in:	Annals of surgical oncology 2012-07, Vol.19 (Suppl 3), p.491-499
Hauptverfasser:	Tsutsumi, Kosuke, Sato, Norihiro, Tanabe, Reiko, Mizumoto, Kazuhiro, Morimatsu, Katsuya, Kayashima, Tadashi, Fujita, Hayato, Ohuchida, Kenoki, Ohtsuka, Takao, Takahata, Shunichi, Nakamura, Masafumi, Tanaka, Masao
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biomarkers, Tumor - metabolism Carcinoma, Pancreatic Ductal - metabolism Carcinoma, Pancreatic Ductal - pathology Carcinoma, Pancreatic Ductal - therapy Cell Line, Tumor Chemotherapy, Adjuvant Claudin-4 - genetics Claudin-4 - metabolism Epithelial Cells - metabolism Female Fibroblasts - metabolism Humans Immunohistochemistry Kaplan-Meier Estimate Male Medicine Medicine & Public Health Middle Aged Multivariate Analysis Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Neoplasm, Residual Oncology Pancreatectomy Pancreatic Ducts Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Pancreatic Neoplasms - therapy Proportional Hazards Models Real-Time Polymerase Chain Reaction RNA, Messenger - metabolism Statistics, Nonparametric Surgery Surgical Oncology Translational Research and Biomarkers
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