Shrinking Lung Syndrome Successfully Treated with Rituximab and Cyclophosphamide

Shrinking lung syndrome (SLS) is an uncommon feature of systemic lupus erythematosus (SLE) characterized by dyspnea, pleuritic chest pain, diaphragmatic elevation, restrictive ventilatory defect and reduced respiratory muscle strength as measured by volitional tests. We report the case of a 28-year-...

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Veröffentlicht in:	Respiration 2012-01, Vol.84 (2), p.144-149
Hauptverfasser:	Langenskiöld, Elisabeth, Bonetti, Alessandro, Fitting, Jean William, Heinzer, Raphaël, Dudler, Jean, Spertini, François, Lazor, Romain
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibodies, Monoclonal, Murine-Derived - administration & dosage Antirheumatic Agents - administration & dosage Autoimmune diseases Chest Pain - etiology Chest Pain - physiopathology Cyclophosphamide - administration & dosage Drug Monitoring - methods Drug therapy Drug Therapy, Combination Dyspnea - etiology Dyspnea - physiopathology Female Humans Lung diseases Lung Diseases - drug therapy Lung Diseases - etiology Lung Diseases - physiopathology Lupus Erythematosus, Systemic - complications Lupus Erythematosus, Systemic - drug therapy Lupus Erythematosus, Systemic - physiopathology Novel Insights from Clinical Practice Pleura - physiopathology Pleurisy - drug therapy Pleurisy - etiology Pleurisy - physiopathology Respiratory Function Tests - methods Respiratory Muscles - physiopathology Rituximab Severity of Illness Index Sjogren's Syndrome - complications Sjogren's Syndrome - drug therapy Sjogren's Syndrome - physiopathology Treatment Outcome
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