Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients
Patients who have received liver transplant are at increased risk of skin complications due to long-term immunosuppression regimen. The aim of this study was to analyze the incidence and risk factors of skin complications in liver transplant patients. We analyzed 161 liver transplant recipients. The...
Gespeichert in:
| Veröffentlicht in: | Acta dermato-venereologica 2012-01, Vol.92 (4), p.411-415 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 415 |
|---|---|
| container_issue | 4 |
| container_start_page | 411 |
| container_title | Acta dermato-venereologica |
| container_volume | 92 |
| creator | BELLONI-FORTINA, Anna PIASERICO, Stefano VITALE, Alessandro ALAIBAC, Mauro BURRA, Patrizia BORDIGNON, Matteo GAMBATO, Martina SENZOLO, Marco RUSSO, Francesco Paolo PESERICO, Andrea DE MATTEIS, Giuseppe PERISSINOTTO, Egle CILLO, Umberto |
| description | Patients who have received liver transplant are at increased risk of skin complications due to long-term immunosuppression regimen. The aim of this study was to analyze the incidence and risk factors of skin complications in liver transplant patients. We analyzed 161 liver transplant recipients. The mean age at transplantation was 47.4 years. Mean follow-up was 6 years. Seventy-one percent of patients presented with skin complications, including aestethic alterations, infections, precancerous lesions and malignancies, which represented 57%, 43%, 18% and 9%, respectively. Risk factors were: age at transplantation ≥ 45 years, immunosuppressive therapy with cyclosporine, and phototype II and III. Our study indicates that although liver transplant recipients are at greater risk of developing skin complications compared to the general population, the risk is lower than for other solid organ transplants, particularly for premalignant and malignant lesions. |
| doi_str_mv | 10.2340/00015555-1316 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1032612081</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1032612081</sourcerecordid><originalsourceid>FETCH-LOGICAL-c362t-9f369e780410e8e43605d1d4021e6eb92cbd7ff8728bc7bb5d375cf7e683b94a3</originalsourceid><addsrcrecordid>eNpFkE1LxDAQhoMo7rp69Cq9CF6i-WiS9ij1ExYWdD2XJJ1itNvWpBX896bsrs5lZngfhuFB6JySa8ZTckMIoSIWppzKAzSnUlDMiFCHaD5leApn6CSEj7gyQbNjNGOMK6VyNUdPr5-uTQrdWvCJbqtkNbzHqRgH3UI3huTOhc5X4EMSuaX7juHa6zb0jW6H5AWs6x20QzhFR7VuApzt-gK9Pdyviye8XD0-F7dLbLlkA85rLnNQGUkpgQxSLomoaJUSRkGCyZk1larrTLHMWGWMqLgStlYgM27yVPMFutre7X33NUIYyo0LFppm-29JCWeSMpLRiOItan0Xgoe67L3baP8ToXKSV-7llZO8yF_sTo9mA9UfvbcVgcsdoIPVTR09WBf-OUnyVAjFfwG7r3Uq</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1032612081</pqid></control><display><type>article</type><title>Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients</title><source>MEDLINE</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><creator>BELLONI-FORTINA, Anna ; PIASERICO, Stefano ; VITALE, Alessandro ; ALAIBAC, Mauro ; BURRA, Patrizia ; BORDIGNON, Matteo ; GAMBATO, Martina ; SENZOLO, Marco ; RUSSO, Francesco Paolo ; PESERICO, Andrea ; DE MATTEIS, Giuseppe ; PERISSINOTTO, Egle ; CILLO, Umberto</creator><creatorcontrib>BELLONI-FORTINA, Anna ; PIASERICO, Stefano ; VITALE, Alessandro ; ALAIBAC, Mauro ; BURRA, Patrizia ; BORDIGNON, Matteo ; GAMBATO, Martina ; SENZOLO, Marco ; RUSSO, Francesco Paolo ; PESERICO, Andrea ; DE MATTEIS, Giuseppe ; PERISSINOTTO, Egle ; CILLO, Umberto</creatorcontrib><description>Patients who have received liver transplant are at increased risk of skin complications due to long-term immunosuppression regimen. The aim of this study was to analyze the incidence and risk factors of skin complications in liver transplant patients. We analyzed 161 liver transplant recipients. The mean age at transplantation was 47.4 years. Mean follow-up was 6 years. Seventy-one percent of patients presented with skin complications, including aestethic alterations, infections, precancerous lesions and malignancies, which represented 57%, 43%, 18% and 9%, respectively. Risk factors were: age at transplantation ≥ 45 years, immunosuppressive therapy with cyclosporine, and phototype II and III. Our study indicates that although liver transplant recipients are at greater risk of developing skin complications compared to the general population, the risk is lower than for other solid organ transplants, particularly for premalignant and malignant lesions.</description><identifier>ISSN: 0001-5555</identifier><identifier>EISSN: 1651-2057</identifier><identifier>DOI: 10.2340/00015555-1316</identifier><identifier>PMID: 22377797</identifier><identifier>CODEN: ADVEA4</identifier><language>eng</language><publisher>Uppsala: Acta dermato-venereologica</publisher><subject>Adult ; Age Factors ; Biological and medical sciences ; Chi-Square Distribution ; Dermatology ; Drug Therapy, Combination ; Humans ; Immunosuppressive Agents - adverse effects ; Incidence ; Italy ; Kaplan-Meier Estimate ; Liver Transplantation - adverse effects ; Logistic Models ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Risk Assessment ; Risk Factors ; Skin Diseases - etiology ; Skin Diseases - prevention & control ; Skin Neoplasms - etiology ; Skin Neoplasms - prevention & control ; Sunlight - adverse effects ; Time Factors ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Acta dermato-venereologica, 2012-01, Vol.92 (4), p.411-415</ispartof><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-9f369e780410e8e43605d1d4021e6eb92cbd7ff8728bc7bb5d375cf7e683b94a3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26094557$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22377797$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>BELLONI-FORTINA, Anna</creatorcontrib><creatorcontrib>PIASERICO, Stefano</creatorcontrib><creatorcontrib>VITALE, Alessandro</creatorcontrib><creatorcontrib>ALAIBAC, Mauro</creatorcontrib><creatorcontrib>BURRA, Patrizia</creatorcontrib><creatorcontrib>BORDIGNON, Matteo</creatorcontrib><creatorcontrib>GAMBATO, Martina</creatorcontrib><creatorcontrib>SENZOLO, Marco</creatorcontrib><creatorcontrib>RUSSO, Francesco Paolo</creatorcontrib><creatorcontrib>PESERICO, Andrea</creatorcontrib><creatorcontrib>DE MATTEIS, Giuseppe</creatorcontrib><creatorcontrib>PERISSINOTTO, Egle</creatorcontrib><creatorcontrib>CILLO, Umberto</creatorcontrib><title>Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients</title><title>Acta dermato-venereologica</title><addtitle>Acta Derm Venereol</addtitle><description>Patients who have received liver transplant are at increased risk of skin complications due to long-term immunosuppression regimen. The aim of this study was to analyze the incidence and risk factors of skin complications in liver transplant patients. We analyzed 161 liver transplant recipients. The mean age at transplantation was 47.4 years. Mean follow-up was 6 years. Seventy-one percent of patients presented with skin complications, including aestethic alterations, infections, precancerous lesions and malignancies, which represented 57%, 43%, 18% and 9%, respectively. Risk factors were: age at transplantation ≥ 45 years, immunosuppressive therapy with cyclosporine, and phototype II and III. Our study indicates that although liver transplant recipients are at greater risk of developing skin complications compared to the general population, the risk is lower than for other solid organ transplants, particularly for premalignant and malignant lesions.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Biological and medical sciences</subject><subject>Chi-Square Distribution</subject><subject>Dermatology</subject><subject>Drug Therapy, Combination</subject><subject>Humans</subject><subject>Immunosuppressive Agents - adverse effects</subject><subject>Incidence</subject><subject>Italy</subject><subject>Kaplan-Meier Estimate</subject><subject>Liver Transplantation - adverse effects</subject><subject>Logistic Models</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Risk Assessment</subject><subject>Risk Factors</subject><subject>Skin Diseases - etiology</subject><subject>Skin Diseases - prevention & control</subject><subject>Skin Neoplasms - etiology</subject><subject>Skin Neoplasms - prevention & control</subject><subject>Sunlight - adverse effects</subject><subject>Time Factors</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>0001-5555</issn><issn>1651-2057</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkE1LxDAQhoMo7rp69Cq9CF6i-WiS9ij1ExYWdD2XJJ1itNvWpBX896bsrs5lZngfhuFB6JySa8ZTckMIoSIWppzKAzSnUlDMiFCHaD5leApn6CSEj7gyQbNjNGOMK6VyNUdPr5-uTQrdWvCJbqtkNbzHqRgH3UI3huTOhc5X4EMSuaX7juHa6zb0jW6H5AWs6x20QzhFR7VuApzt-gK9Pdyviye8XD0-F7dLbLlkA85rLnNQGUkpgQxSLomoaJUSRkGCyZk1larrTLHMWGWMqLgStlYgM27yVPMFutre7X33NUIYyo0LFppm-29JCWeSMpLRiOItan0Xgoe67L3baP8ToXKSV-7llZO8yF_sTo9mA9UfvbcVgcsdoIPVTR09WBf-OUnyVAjFfwG7r3Uq</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>BELLONI-FORTINA, Anna</creator><creator>PIASERICO, Stefano</creator><creator>VITALE, Alessandro</creator><creator>ALAIBAC, Mauro</creator><creator>BURRA, Patrizia</creator><creator>BORDIGNON, Matteo</creator><creator>GAMBATO, Martina</creator><creator>SENZOLO, Marco</creator><creator>RUSSO, Francesco Paolo</creator><creator>PESERICO, Andrea</creator><creator>DE MATTEIS, Giuseppe</creator><creator>PERISSINOTTO, Egle</creator><creator>CILLO, Umberto</creator><general>Acta dermato-venereologica</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120101</creationdate><title>Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients</title><author>BELLONI-FORTINA, Anna ; PIASERICO, Stefano ; VITALE, Alessandro ; ALAIBAC, Mauro ; BURRA, Patrizia ; BORDIGNON, Matteo ; GAMBATO, Martina ; SENZOLO, Marco ; RUSSO, Francesco Paolo ; PESERICO, Andrea ; DE MATTEIS, Giuseppe ; PERISSINOTTO, Egle ; CILLO, Umberto</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-9f369e780410e8e43605d1d4021e6eb92cbd7ff8728bc7bb5d375cf7e683b94a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Biological and medical sciences</topic><topic>Chi-Square Distribution</topic><topic>Dermatology</topic><topic>Drug Therapy, Combination</topic><topic>Humans</topic><topic>Immunosuppressive Agents - adverse effects</topic><topic>Incidence</topic><topic>Italy</topic><topic>Kaplan-Meier Estimate</topic><topic>Liver Transplantation - adverse effects</topic><topic>Logistic Models</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Risk Assessment</topic><topic>Risk Factors</topic><topic>Skin Diseases - etiology</topic><topic>Skin Diseases - prevention & control</topic><topic>Skin Neoplasms - etiology</topic><topic>Skin Neoplasms - prevention & control</topic><topic>Sunlight - adverse effects</topic><topic>Time Factors</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BELLONI-FORTINA, Anna</creatorcontrib><creatorcontrib>PIASERICO, Stefano</creatorcontrib><creatorcontrib>VITALE, Alessandro</creatorcontrib><creatorcontrib>ALAIBAC, Mauro</creatorcontrib><creatorcontrib>BURRA, Patrizia</creatorcontrib><creatorcontrib>BORDIGNON, Matteo</creatorcontrib><creatorcontrib>GAMBATO, Martina</creatorcontrib><creatorcontrib>SENZOLO, Marco</creatorcontrib><creatorcontrib>RUSSO, Francesco Paolo</creatorcontrib><creatorcontrib>PESERICO, Andrea</creatorcontrib><creatorcontrib>DE MATTEIS, Giuseppe</creatorcontrib><creatorcontrib>PERISSINOTTO, Egle</creatorcontrib><creatorcontrib>CILLO, Umberto</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Acta dermato-venereologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BELLONI-FORTINA, Anna</au><au>PIASERICO, Stefano</au><au>VITALE, Alessandro</au><au>ALAIBAC, Mauro</au><au>BURRA, Patrizia</au><au>BORDIGNON, Matteo</au><au>GAMBATO, Martina</au><au>SENZOLO, Marco</au><au>RUSSO, Francesco Paolo</au><au>PESERICO, Andrea</au><au>DE MATTEIS, Giuseppe</au><au>PERISSINOTTO, Egle</au><au>CILLO, Umberto</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients</atitle><jtitle>Acta dermato-venereologica</jtitle><addtitle>Acta Derm Venereol</addtitle><date>2012-01-01</date><risdate>2012</risdate><volume>92</volume><issue>4</issue><spage>411</spage><epage>415</epage><pages>411-415</pages><issn>0001-5555</issn><eissn>1651-2057</eissn><coden>ADVEA4</coden><abstract>Patients who have received liver transplant are at increased risk of skin complications due to long-term immunosuppression regimen. The aim of this study was to analyze the incidence and risk factors of skin complications in liver transplant patients. We analyzed 161 liver transplant recipients. The mean age at transplantation was 47.4 years. Mean follow-up was 6 years. Seventy-one percent of patients presented with skin complications, including aestethic alterations, infections, precancerous lesions and malignancies, which represented 57%, 43%, 18% and 9%, respectively. Risk factors were: age at transplantation ≥ 45 years, immunosuppressive therapy with cyclosporine, and phototype II and III. Our study indicates that although liver transplant recipients are at greater risk of developing skin complications compared to the general population, the risk is lower than for other solid organ transplants, particularly for premalignant and malignant lesions.</abstract><cop>Uppsala</cop><pub>Acta dermato-venereologica</pub><pmid>22377797</pmid><doi>10.2340/00015555-1316</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-5555 |
| ispartof | Acta dermato-venereologica, 2012-01, Vol.92 (4), p.411-415 |
| issn | 0001-5555 1651-2057 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1032612081 |
| source | MEDLINE; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection |
| subjects | Adult Age Factors Biological and medical sciences Chi-Square Distribution Dermatology Drug Therapy, Combination Humans Immunosuppressive Agents - adverse effects Incidence Italy Kaplan-Meier Estimate Liver Transplantation - adverse effects Logistic Models Medical sciences Middle Aged Multivariate Analysis Risk Assessment Risk Factors Skin Diseases - etiology Skin Diseases - prevention & control Skin Neoplasms - etiology Skin Neoplasms - prevention & control Sunlight - adverse effects Time Factors Tumors of the skin and soft tissue. Premalignant lesions |
| title | Skin Cancer and Other Cutaneous Disorders in Liver Transplant Recipients |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-10T15%3A07%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Skin%20Cancer%20and%20Other%20Cutaneous%20Disorders%20in%20Liver%20Transplant%20Recipients&rft.jtitle=Acta%20dermato-venereologica&rft.au=BELLONI-FORTINA,%20Anna&rft.date=2012-01-01&rft.volume=92&rft.issue=4&rft.spage=411&rft.epage=415&rft.pages=411-415&rft.issn=0001-5555&rft.eissn=1651-2057&rft.coden=ADVEA4&rft_id=info:doi/10.2340/00015555-1316&rft_dat=%3Cproquest_cross%3E1032612081%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1032612081&rft_id=info:pmid/22377797&rfr_iscdi=true |