A case of autoimmune pancreatitis with multifocal mass lesions

We present a case of a 73-year-old man with multifocal autoimmune pancreatitis (AIP) in the pancreatic head and tail, and who had undergone sigmoidectomy and rectectomy 28 months before presenting to our department. Upon presentation, his serum IgG4 level was elevated at 267mg/dl, but tumor marker l...

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Veröffentlicht in:Nippon Shokakibyo Gakkai Zasshi 2012, Vol.109(8), pp.1409-1418
Hauptverfasser: HIRAMATSU, Shinsuke, NEBIKI, Hiroko, UENO, Ayako, MARUYAMA, Hirotsugu, SUEKANE, Takehisa, YAMASAKI, Tomoaki, SASAKI, Eiji, SANO, Koji, SATO, Hiroshi
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container_end_page 1418
container_issue 8
container_start_page 1409
container_title Nippon Shokakibyo Gakkai Zasshi
container_volume 109
creator HIRAMATSU, Shinsuke
NEBIKI, Hiroko
UENO, Ayako
MARUYAMA, Hirotsugu
SUEKANE, Takehisa
YAMASAKI, Tomoaki
SASAKI, Eiji
SANO, Koji
SATO, Hiroshi
description We present a case of a 73-year-old man with multifocal autoimmune pancreatitis (AIP) in the pancreatic head and tail, and who had undergone sigmoidectomy and rectectomy 28 months before presenting to our department. Upon presentation, his serum IgG4 level was elevated at 267mg/dl, but tumor marker levels were within normal ranges. CT and MRI showed two localized pancreatic masses with delayed enhancement, but endoscopic retrograde pancreatography revealed neither stenosis nor dilatation of the main pancreatic duct. FDG-PET examination showed intense uptake in regions concordant with both tumors. The possibility of atypical AIP was a concern, but malignant tumor could not be clinically or radiologically excluded. Endoscopic ultrasonographic fine-needle aspiration biopsy was performed, but no malignant cells were detected. The patient underwent subsequent distal pancreatectomy. Histological evaluation of the tumors showed the presence of many IgG4-positive plasma cells without any evidence of malignancy.
doi_str_mv 10.11405/nisshoshi.109.1409
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subjects Aged
Autoimmune Diseases - pathology
Humans
Male
Pancreatitis - pathology
Pancreatitis - surgery
Postoperative Complications
Rectal Neoplasms - surgery
Sigmoid Neoplasms - surgery
title A case of autoimmune pancreatitis with multifocal mass lesions
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