Basic Potential of Carbon Nanotubes in Tissue Engineering Applications
Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved...
Gespeichert in:
| Veröffentlicht in: | Journal of nanomaterials 2012-01, Vol.2012 (2012), p.1-10 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 10 |
|---|---|
| container_issue | 2012 |
| container_start_page | 1 |
| container_title | Journal of nanomaterials |
| container_volume | 2012 |
| creator | Shimizu, Masayuki Ogihara, Nobuhide Okamoto, Masanori Kobayashi, Shinsuke Ishigaki, Norio Nakamura, Koichi Kato, Hiroyuki Aoki, Kaoru Hara, Kazuo Narita, Nobuyo Usui, Yuki Tsukahara, Tamotsu Matsuda, Yoshikazu Saito, Naoto Haniu, Hisao Takanashi, Seiji |
| description | Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs) in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups. |
| doi_str_mv | 10.1155/2012/343747 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1031333591</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1031333591</sourcerecordid><originalsourceid>FETCH-LOGICAL-a572t-a4a06182451f61b5f8484cd11227fc3b25bc5ef42c5b09997cb0d6e7cb7b83cf3</originalsourceid><addsrcrecordid>eNqF0E1LAzEQBuAgCtbqybsEvIiyNp_7caylVaGoh3pekjSpKdtkTXYR_70pKyJeZA4zh4eZ4QXgHKNbjDmfEITJhDJasOIAjHBeFhnDpDr8mTE6BicxbhFivOJkBBZ3IloFX3ynXWdFA72BMxGkd_BJON_1UkdoHVzZGHsN525jndbBug2ctm1jleisd_EUHBnRRH323cfgdTFfzR6y5fP942y6zAQvSJcJJlCOS8I4NjmW3JSsZGqNMSGFUVQSLhXXhhHFJaqqqlASrXOdWiFLqgwdg6thbxv8e69jV-9sVLpphNO-jzVGFFNKeYUTvfxDt74PLn2XVKo8nS6SuhmUCj7GoE3dBrsT4TOhep9pvc-0HjJN-nrQb9atxYf9B18MWCeijfiFSYXLnH4BFbN-Mw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1010164847</pqid></control><display><type>article</type><title>Basic Potential of Carbon Nanotubes in Tissue Engineering Applications</title><source>Wiley Online Library Open Access</source><source>EZB-FREE-00999 freely available EZB journals</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><creator>Shimizu, Masayuki ; Ogihara, Nobuhide ; Okamoto, Masanori ; Kobayashi, Shinsuke ; Ishigaki, Norio ; Nakamura, Koichi ; Kato, Hiroyuki ; Aoki, Kaoru ; Hara, Kazuo ; Narita, Nobuyo ; Usui, Yuki ; Tsukahara, Tamotsu ; Matsuda, Yoshikazu ; Saito, Naoto ; Haniu, Hisao ; Takanashi, Seiji</creator><contributor>Verdejo, Raquel</contributor><creatorcontrib>Shimizu, Masayuki ; Ogihara, Nobuhide ; Okamoto, Masanori ; Kobayashi, Shinsuke ; Ishigaki, Norio ; Nakamura, Koichi ; Kato, Hiroyuki ; Aoki, Kaoru ; Hara, Kazuo ; Narita, Nobuyo ; Usui, Yuki ; Tsukahara, Tamotsu ; Matsuda, Yoshikazu ; Saito, Naoto ; Haniu, Hisao ; Takanashi, Seiji ; Verdejo, Raquel</creatorcontrib><description>Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs) in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.</description><identifier>ISSN: 1687-4110</identifier><identifier>EISSN: 1687-4129</identifier><identifier>DOI: 10.1155/2012/343747</identifier><language>eng</language><publisher>Cairo, Egypt: Hindawi Publishing Corporation</publisher><subject>Asbestos ; Biomedical materials ; Carbon ; Cytotoxicity ; Health sciences ; Materials science ; Nanomaterials ; Nanotubes ; Physical properties ; Respiratory system ; Studies ; Toxicity ; Vaccines</subject><ispartof>Journal of nanomaterials, 2012-01, Vol.2012 (2012), p.1-10</ispartof><rights>Copyright © 2012 Hisao Haniu et al.</rights><rights>Copyright © 2012 Hisao Haniu et al. Hisao Haniu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a572t-a4a06182451f61b5f8484cd11227fc3b25bc5ef42c5b09997cb0d6e7cb7b83cf3</citedby><cites>FETCH-LOGICAL-a572t-a4a06182451f61b5f8484cd11227fc3b25bc5ef42c5b09997cb0d6e7cb7b83cf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><contributor>Verdejo, Raquel</contributor><creatorcontrib>Shimizu, Masayuki</creatorcontrib><creatorcontrib>Ogihara, Nobuhide</creatorcontrib><creatorcontrib>Okamoto, Masanori</creatorcontrib><creatorcontrib>Kobayashi, Shinsuke</creatorcontrib><creatorcontrib>Ishigaki, Norio</creatorcontrib><creatorcontrib>Nakamura, Koichi</creatorcontrib><creatorcontrib>Kato, Hiroyuki</creatorcontrib><creatorcontrib>Aoki, Kaoru</creatorcontrib><creatorcontrib>Hara, Kazuo</creatorcontrib><creatorcontrib>Narita, Nobuyo</creatorcontrib><creatorcontrib>Usui, Yuki</creatorcontrib><creatorcontrib>Tsukahara, Tamotsu</creatorcontrib><creatorcontrib>Matsuda, Yoshikazu</creatorcontrib><creatorcontrib>Saito, Naoto</creatorcontrib><creatorcontrib>Haniu, Hisao</creatorcontrib><creatorcontrib>Takanashi, Seiji</creatorcontrib><title>Basic Potential of Carbon Nanotubes in Tissue Engineering Applications</title><title>Journal of nanomaterials</title><description>Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs) in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.</description><subject>Asbestos</subject><subject>Biomedical materials</subject><subject>Carbon</subject><subject>Cytotoxicity</subject><subject>Health sciences</subject><subject>Materials science</subject><subject>Nanomaterials</subject><subject>Nanotubes</subject><subject>Physical properties</subject><subject>Respiratory system</subject><subject>Studies</subject><subject>Toxicity</subject><subject>Vaccines</subject><issn>1687-4110</issn><issn>1687-4129</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>RHX</sourceid><sourceid>BENPR</sourceid><recordid>eNqF0E1LAzEQBuAgCtbqybsEvIiyNp_7caylVaGoh3pekjSpKdtkTXYR_70pKyJeZA4zh4eZ4QXgHKNbjDmfEITJhDJasOIAjHBeFhnDpDr8mTE6BicxbhFivOJkBBZ3IloFX3ynXWdFA72BMxGkd_BJON_1UkdoHVzZGHsN525jndbBug2ctm1jleisd_EUHBnRRH323cfgdTFfzR6y5fP942y6zAQvSJcJJlCOS8I4NjmW3JSsZGqNMSGFUVQSLhXXhhHFJaqqqlASrXOdWiFLqgwdg6thbxv8e69jV-9sVLpphNO-jzVGFFNKeYUTvfxDt74PLn2XVKo8nS6SuhmUCj7GoE3dBrsT4TOhep9pvc-0HjJN-nrQb9atxYf9B18MWCeijfiFSYXLnH4BFbN-Mw</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Shimizu, Masayuki</creator><creator>Ogihara, Nobuhide</creator><creator>Okamoto, Masanori</creator><creator>Kobayashi, Shinsuke</creator><creator>Ishigaki, Norio</creator><creator>Nakamura, Koichi</creator><creator>Kato, Hiroyuki</creator><creator>Aoki, Kaoru</creator><creator>Hara, Kazuo</creator><creator>Narita, Nobuyo</creator><creator>Usui, Yuki</creator><creator>Tsukahara, Tamotsu</creator><creator>Matsuda, Yoshikazu</creator><creator>Saito, Naoto</creator><creator>Haniu, Hisao</creator><creator>Takanashi, Seiji</creator><general>Hindawi Publishing Corporation</general><general>Hindawi Limited</general><scope>ADJCN</scope><scope>AHFXO</scope><scope>RHU</scope><scope>RHW</scope><scope>RHX</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>8FE</scope><scope>8FG</scope><scope>ABJCF</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>CWDGH</scope><scope>D1I</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>JG9</scope><scope>KB.</scope><scope>L7M</scope><scope>PDBOC</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7QO</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20120101</creationdate><title>Basic Potential of Carbon Nanotubes in Tissue Engineering Applications</title><author>Shimizu, Masayuki ; Ogihara, Nobuhide ; Okamoto, Masanori ; Kobayashi, Shinsuke ; Ishigaki, Norio ; Nakamura, Koichi ; Kato, Hiroyuki ; Aoki, Kaoru ; Hara, Kazuo ; Narita, Nobuyo ; Usui, Yuki ; Tsukahara, Tamotsu ; Matsuda, Yoshikazu ; Saito, Naoto ; Haniu, Hisao ; Takanashi, Seiji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a572t-a4a06182451f61b5f8484cd11227fc3b25bc5ef42c5b09997cb0d6e7cb7b83cf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Asbestos</topic><topic>Biomedical materials</topic><topic>Carbon</topic><topic>Cytotoxicity</topic><topic>Health sciences</topic><topic>Materials science</topic><topic>Nanomaterials</topic><topic>Nanotubes</topic><topic>Physical properties</topic><topic>Respiratory system</topic><topic>Studies</topic><topic>Toxicity</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shimizu, Masayuki</creatorcontrib><creatorcontrib>Ogihara, Nobuhide</creatorcontrib><creatorcontrib>Okamoto, Masanori</creatorcontrib><creatorcontrib>Kobayashi, Shinsuke</creatorcontrib><creatorcontrib>Ishigaki, Norio</creatorcontrib><creatorcontrib>Nakamura, Koichi</creatorcontrib><creatorcontrib>Kato, Hiroyuki</creatorcontrib><creatorcontrib>Aoki, Kaoru</creatorcontrib><creatorcontrib>Hara, Kazuo</creatorcontrib><creatorcontrib>Narita, Nobuyo</creatorcontrib><creatorcontrib>Usui, Yuki</creatorcontrib><creatorcontrib>Tsukahara, Tamotsu</creatorcontrib><creatorcontrib>Matsuda, Yoshikazu</creatorcontrib><creatorcontrib>Saito, Naoto</creatorcontrib><creatorcontrib>Haniu, Hisao</creatorcontrib><creatorcontrib>Takanashi, Seiji</creatorcontrib><collection>الدوريات العلمية والإحصائية - e-Marefa Academic and Statistical Periodicals</collection><collection>معرفة - المحتوى العربي الأكاديمي المتكامل - e-Marefa Academic Complete</collection><collection>Hindawi Publishing Complete</collection><collection>Hindawi Publishing Subscription Journals</collection><collection>Hindawi Publishing Open Access</collection><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Technology Collection</collection><collection>Materials Science & Engineering Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Technology Collection</collection><collection>ProQuest One Community College</collection><collection>Middle East & Africa Database</collection><collection>ProQuest Materials Science Collection</collection><collection>ProQuest Central Korea</collection><collection>SciTech Premium Collection</collection><collection>Materials Research Database</collection><collection>Materials Science Database</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Materials Science Collection</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>Biotechnology Research Abstracts</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Journal of nanomaterials</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shimizu, Masayuki</au><au>Ogihara, Nobuhide</au><au>Okamoto, Masanori</au><au>Kobayashi, Shinsuke</au><au>Ishigaki, Norio</au><au>Nakamura, Koichi</au><au>Kato, Hiroyuki</au><au>Aoki, Kaoru</au><au>Hara, Kazuo</au><au>Narita, Nobuyo</au><au>Usui, Yuki</au><au>Tsukahara, Tamotsu</au><au>Matsuda, Yoshikazu</au><au>Saito, Naoto</au><au>Haniu, Hisao</au><au>Takanashi, Seiji</au><au>Verdejo, Raquel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Basic Potential of Carbon Nanotubes in Tissue Engineering Applications</atitle><jtitle>Journal of nanomaterials</jtitle><date>2012-01-01</date><risdate>2012</risdate><volume>2012</volume><issue>2012</issue><spage>1</spage><epage>10</epage><pages>1-10</pages><issn>1687-4110</issn><eissn>1687-4129</eissn><abstract>Carbon nanotubes (CNTs) are attracting interest in various fields of science because they possess a high surface area-to-volume ratio and excellent electronic, mechanical, and thermal properties. Various medical applications of CNTs are expected, and the properties of CNTs have been greatly improved for use in biomaterials. However, the safety of CNTs remains unclear, which impedes their medical application. Our group is evaluating the biological responses of multiwall CNTs (MWCNTs) in vivo and in vitro for the promotion of tissue regeneration as safe scaffold materials. We recently showed that intracellular accumulation is important for the cytotoxicity of CNTs, and we reported the active physiological functions CNTs in cells. In this review, we describe the effects of CNTs in vivo and in vitro observed by our group from the standpoint of tissue engineering, and we introduce the findings of other research groups.</abstract><cop>Cairo, Egypt</cop><pub>Hindawi Publishing Corporation</pub><doi>10.1155/2012/343747</doi><tpages>10</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1687-4110 |
| ispartof | Journal of nanomaterials, 2012-01, Vol.2012 (2012), p.1-10 |
| issn | 1687-4110 1687-4129 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1031333591 |
| source | Wiley Online Library Open Access; EZB-FREE-00999 freely available EZB journals; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | Asbestos Biomedical materials Carbon Cytotoxicity Health sciences Materials science Nanomaterials Nanotubes Physical properties Respiratory system Studies Toxicity Vaccines |
| title | Basic Potential of Carbon Nanotubes in Tissue Engineering Applications |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-29T01%3A16%3A11IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Basic%20Potential%20of%20Carbon%20Nanotubes%20in%20Tissue%20Engineering%20Applications&rft.jtitle=Journal%20of%20nanomaterials&rft.au=Shimizu,%20Masayuki&rft.date=2012-01-01&rft.volume=2012&rft.issue=2012&rft.spage=1&rft.epage=10&rft.pages=1-10&rft.issn=1687-4110&rft.eissn=1687-4129&rft_id=info:doi/10.1155/2012/343747&rft_dat=%3Cproquest_cross%3E1031333591%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1010164847&rft_id=info:pmid/&rfr_iscdi=true |