Delivery of large molecules via poly(butyl cyanoacrylate) nanoparticles into the injured rat brain

Poly(n-butyl-2-cyanoacrylate) (PBCA) nanoparticles have been successfully applied to deliver small-molecule drugs to the central nervous system (CNS). However, it is unclear whether PBCA nanoparticles can be used as the delivery system for large molecules to potentially treat traumatic brain injury...

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Veröffentlicht in:	Nanotechnology 2012-04, Vol.23 (16), p.165101-1-8
Hauptverfasser:	Lin, Yong, Pan, Yaohua, Shi, Yinfeng, Huang, Xianjian, Jia, Nengqin, Jiang, Ji-yao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blood-Brain Barrier - chemistry Brain Injuries - metabolism Diffusion Enbucrilate - chemistry Male Multiprotein Complexes - chemistry Nanocapsules - chemistry Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
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