Targeting neuronal adenylyl cyclase for the treatment of chronic pain

Pain research is currently undergoing dramatic changes. In the area of basic pain research, new discoveries have been made towards the understanding of pain transmission, modulation and plasticity. However, many of these basic discoveries have not yet led to the development of new drugs for the trea...

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Veröffentlicht in:	Drug discovery today 2012-06, Vol.17 (11-12), p.573-582
1. Verfasser:	Zhuo, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - analogs & derivatives Adenosine Triphosphate - pharmacology Adenosine Triphosphate - therapeutic use Adenylyl Cyclase Inhibitors Adenylyl Cyclases Analgesics - pharmacology Analgesics - therapeutic use Animals Biological and medical sciences Cerebral Cortex - drug effects Chronic Pain - drug therapy Chronic Pain - enzymology Chronic Pain - etiology Chronic Pain - genetics Drug Discovery General pharmacology Humans Long-Term Potentiation - drug effects Medical sciences Molecular Targeted Therapy Neurons - drug effects Neurons - enzymology Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Synaptic Potentials - drug effects
Online-Zugang:	Volltext
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