A microfluidic-based electrochemical biochip for label-free diffusion-restricted DNA hybridization analysis

DNA hybridization detection in microfluidic devices can reduce sample volumes, processing times, and can be integrated with other measurements. However, as device footprints decrease and their complexity increase, the signal-to-noise ratio in these systems also decreases and the sensitivity is there...

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Veröffentlicht in:	Biosensors & bioelectronics 2012-10, Vol.38 (1), p.114-120
Hauptverfasser:	Ben-Yoav, Hadar, Dykstra, Peter H., Bentley, William E., Ghodssi, Reza
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochip Biological and medical sciences Biosensing Techniques - instrumentation Biosensors Biotechnology Diffusion DNA hybridization biosensor DNA, Single-Stranded - analysis Electrochemical impedance spectroscopy Electrochemical Techniques - instrumentation Fundamental and applied biological sciences. Psychology Label-free detection Limit of Detection Methods. Procedures. Technologies Microfluidic Analytical Techniques - instrumentation Microfluidics Oligonucleotide Array Sequence Analysis - instrumentation Restricted diffusion Various methods and equipments
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