Circulating microRNA profiles reflect the presence of breast tumours but not the profiles of microRNAs within the tumours

Background Extra-cellular microRNAs have been identified within blood and their profiles reflect various pathologies; therefore they have potential as disease biomarkers. Our aim was to investigate how circulating microRNA profiles change during cancer treatment. Our hypothesis was that tumour-relat...

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Veröffentlicht in:	Cellular oncology (Dordrecht) 2012-08, Vol.35 (4), p.301-308
Hauptverfasser:	Cookson, Victoria J., Bentley, Michael A., Hogan, Brian V., Horgan, Kieran, Hayward, Bruce E., Hazelwood, Lee D., Hughes, Thomas A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - blood Biomarkers, Tumor - genetics Biomedical and Life Sciences Biomedicine Breast Neoplasms - blood Breast Neoplasms - genetics Breast Neoplasms - surgery Cancer Research Female Gene Expression Profiling Humans MicroRNAs - blood MicroRNAs - genetics Oncology Original Paper Pathology Postoperative Period Preoperative Period Prospective Studies Reverse Transcriptase Polymerase Chain Reaction Time Factors
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