Bilateral Mucinous Cystadenomas and Massive Edema of the Ovaries in a Virilized Adolescent Girl
Ovarian pathology, including nonfunctional tumors and massive edema of the ovary, has been associated with stromal luteinization and clinical endocrinopathies. An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation revealed an elevat...
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Veröffentlicht in: | Obstetrics and gynecology (New York. 1953) 2012-08, Vol.120 (Suppl 2), p.473-476 |
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creator | Thomas, Robin L. Carr, Bruce R. Ziadie, Mandolin S. Wilson, Ellen E. |
description | Ovarian pathology, including nonfunctional tumors and massive edema of the ovary, has been associated with stromal luteinization and clinical endocrinopathies.
An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation revealed an elevated serum total testosterone level of 241 ng/dL. Magnetic resonance imaging confirmed three cystic adnexal structures, with the largest measuring 16 × 8 × 18 cm. Surgery with pelvic washings, bilateral ovarian cystectomies, unilateral paratubal cystectomy, and bilateral ovarian biopsies were performed. Pathology confirmed bilateral mucinous cystadenomas and massive edema of the ovaries. Postoperatively, the serum total testosterone level normalized.
Nonfunctional ovarian tumors and massive edema of the ovaries should be considered in the differential diagnosis for a patient presenting with signs of hyperandrogenism. |
doi_str_mv | 10.1097/AOG.0b013e3182572654 |
format | Article |
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An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation revealed an elevated serum total testosterone level of 241 ng/dL. Magnetic resonance imaging confirmed three cystic adnexal structures, with the largest measuring 16 × 8 × 18 cm. Surgery with pelvic washings, bilateral ovarian cystectomies, unilateral paratubal cystectomy, and bilateral ovarian biopsies were performed. Pathology confirmed bilateral mucinous cystadenomas and massive edema of the ovaries. Postoperatively, the serum total testosterone level normalized.
Nonfunctional ovarian tumors and massive edema of the ovaries should be considered in the differential diagnosis for a patient presenting with signs of hyperandrogenism.</description><identifier>ISSN: 0029-7844</identifier><identifier>EISSN: 1873-233X</identifier><identifier>DOI: 10.1097/AOG.0b013e3182572654</identifier><identifier>PMID: 22825270</identifier><identifier>CODEN: OBGNAS</identifier><language>eng</language><publisher>Hagerstown, MD: The American College of Obstetricians and Gynecologists</publisher><subject>Adolescent ; Amenorrhea - etiology ; Biological and medical sciences ; Cystadenoma, Mucinous - pathology ; Cystadenoma, Mucinous - surgery ; Drainage ; Edema - pathology ; Edema - surgery ; Female ; Gynecology. Andrology. Obstetrics ; Humans ; Hyperandrogenism - diagnosis ; Magnetic Resonance Imaging ; Medical sciences ; Ovarian Diseases - pathology ; Ovarian Diseases - surgery ; Ovarian Neoplasms - pathology ; Ovarian Neoplasms - surgery ; Testosterone - blood ; Tomography, X-Ray Computed ; Virilism - diagnosis</subject><ispartof>Obstetrics and gynecology (New York. 1953), 2012-08, Vol.120 (Suppl 2), p.473-476</ispartof><rights>The American College of Obstetricians and Gynecologists</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3824-6f14a61c7ad35da9def273bea8f3e1da889d59a912da98f1a7749e27ef77602d3</citedby><cites>FETCH-LOGICAL-c3824-6f14a61c7ad35da9def273bea8f3e1da889d59a912da98f1a7749e27ef77602d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26184457$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22825270$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thomas, Robin L.</creatorcontrib><creatorcontrib>Carr, Bruce R.</creatorcontrib><creatorcontrib>Ziadie, Mandolin S.</creatorcontrib><creatorcontrib>Wilson, Ellen E.</creatorcontrib><title>Bilateral Mucinous Cystadenomas and Massive Edema of the Ovaries in a Virilized Adolescent Girl</title><title>Obstetrics and gynecology (New York. 1953)</title><addtitle>Obstet Gynecol</addtitle><description>Ovarian pathology, including nonfunctional tumors and massive edema of the ovary, has been associated with stromal luteinization and clinical endocrinopathies.
An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation revealed an elevated serum total testosterone level of 241 ng/dL. Magnetic resonance imaging confirmed three cystic adnexal structures, with the largest measuring 16 × 8 × 18 cm. Surgery with pelvic washings, bilateral ovarian cystectomies, unilateral paratubal cystectomy, and bilateral ovarian biopsies were performed. Pathology confirmed bilateral mucinous cystadenomas and massive edema of the ovaries. Postoperatively, the serum total testosterone level normalized.
Nonfunctional ovarian tumors and massive edema of the ovaries should be considered in the differential diagnosis for a patient presenting with signs of hyperandrogenism.</description><subject>Adolescent</subject><subject>Amenorrhea - etiology</subject><subject>Biological and medical sciences</subject><subject>Cystadenoma, Mucinous - pathology</subject><subject>Cystadenoma, Mucinous - surgery</subject><subject>Drainage</subject><subject>Edema - pathology</subject><subject>Edema - surgery</subject><subject>Female</subject><subject>Gynecology. Andrology. Obstetrics</subject><subject>Humans</subject><subject>Hyperandrogenism - diagnosis</subject><subject>Magnetic Resonance Imaging</subject><subject>Medical sciences</subject><subject>Ovarian Diseases - pathology</subject><subject>Ovarian Diseases - surgery</subject><subject>Ovarian Neoplasms - pathology</subject><subject>Ovarian Neoplasms - surgery</subject><subject>Testosterone - blood</subject><subject>Tomography, X-Ray Computed</subject><subject>Virilism - diagnosis</subject><issn>0029-7844</issn><issn>1873-233X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkcFu1DAQhi0EokvhDRDyBYlLythOYue4rMpSqdVeAHGzZuOx1uAkxU5alafHVZdW4uSDv9_j-X7G3go4E9Dpj-vd9gz2IBQpYWSjZdvUz9hKGK0qqdSP52wFILtKm7o-Ya9y_gkAou3US3YiZUlIDStmP4WIMyWM_GrpwzgtmW_u8oyOxmnAzHF0_ApzDjfEzx0NyCfP5wPx3Q2mQJmHkSP_HlKI4Q85vnZTpNzTOPNtSPE1e-ExZnpzPE_Zt8_nXzdfqsvd9mKzvqx6ZWRdtV7U2Ipeo1ONw86Rl1rtCY1XJBwa07mmw07Icmm8QK3rjqQmr3UL0qlT9uHh3es0_V4oz3YI5Rcx4khlJytAQQPSaFHQ-gHt05RzIm-vUxgw3RXI3qu1Ra39X22JvTtOWPYDucfQP5cFeH8EMPcYfcKxD_mJa0VpotFP82-nWMznX3G5pWQPhHE-2FIStLKBSoKQYEpl1X1vtfoLzVyRdg</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Thomas, Robin L.</creator><creator>Carr, Bruce R.</creator><creator>Ziadie, Mandolin S.</creator><creator>Wilson, Ellen E.</creator><general>The American College of Obstetricians and Gynecologists</general><general>Lippincott Williams & Wilkins</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>Bilateral Mucinous Cystadenomas and Massive Edema of the Ovaries in a Virilized Adolescent Girl</title><author>Thomas, Robin L. ; Carr, Bruce R. ; Ziadie, Mandolin S. ; Wilson, Ellen E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3824-6f14a61c7ad35da9def273bea8f3e1da889d59a912da98f1a7749e27ef77602d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Amenorrhea - etiology</topic><topic>Biological and medical sciences</topic><topic>Cystadenoma, Mucinous - pathology</topic><topic>Cystadenoma, Mucinous - surgery</topic><topic>Drainage</topic><topic>Edema - pathology</topic><topic>Edema - surgery</topic><topic>Female</topic><topic>Gynecology. Andrology. Obstetrics</topic><topic>Humans</topic><topic>Hyperandrogenism - diagnosis</topic><topic>Magnetic Resonance Imaging</topic><topic>Medical sciences</topic><topic>Ovarian Diseases - pathology</topic><topic>Ovarian Diseases - surgery</topic><topic>Ovarian Neoplasms - pathology</topic><topic>Ovarian Neoplasms - surgery</topic><topic>Testosterone - blood</topic><topic>Tomography, X-Ray Computed</topic><topic>Virilism - diagnosis</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thomas, Robin L.</creatorcontrib><creatorcontrib>Carr, Bruce R.</creatorcontrib><creatorcontrib>Ziadie, Mandolin S.</creatorcontrib><creatorcontrib>Wilson, Ellen E.</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thomas, Robin L.</au><au>Carr, Bruce R.</au><au>Ziadie, Mandolin S.</au><au>Wilson, Ellen E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Bilateral Mucinous Cystadenomas and Massive Edema of the Ovaries in a Virilized Adolescent Girl</atitle><jtitle>Obstetrics and gynecology (New York. 1953)</jtitle><addtitle>Obstet Gynecol</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>120</volume><issue>Suppl 2</issue><spage>473</spage><epage>476</epage><pages>473-476</pages><issn>0029-7844</issn><eissn>1873-233X</eissn><coden>OBGNAS</coden><abstract>Ovarian pathology, including nonfunctional tumors and massive edema of the ovary, has been associated with stromal luteinization and clinical endocrinopathies.
An adolescent girl presented with primary amenorrhea, clitoromegaly, and large abdominopelvic mass. Laboratory evaluation revealed an elevated serum total testosterone level of 241 ng/dL. Magnetic resonance imaging confirmed three cystic adnexal structures, with the largest measuring 16 × 8 × 18 cm. Surgery with pelvic washings, bilateral ovarian cystectomies, unilateral paratubal cystectomy, and bilateral ovarian biopsies were performed. Pathology confirmed bilateral mucinous cystadenomas and massive edema of the ovaries. Postoperatively, the serum total testosterone level normalized.
Nonfunctional ovarian tumors and massive edema of the ovaries should be considered in the differential diagnosis for a patient presenting with signs of hyperandrogenism.</abstract><cop>Hagerstown, MD</cop><pub>The American College of Obstetricians and Gynecologists</pub><pmid>22825270</pmid><doi>10.1097/AOG.0b013e3182572654</doi><tpages>4</tpages></addata></record> |
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subjects | Adolescent Amenorrhea - etiology Biological and medical sciences Cystadenoma, Mucinous - pathology Cystadenoma, Mucinous - surgery Drainage Edema - pathology Edema - surgery Female Gynecology. Andrology. Obstetrics Humans Hyperandrogenism - diagnosis Magnetic Resonance Imaging Medical sciences Ovarian Diseases - pathology Ovarian Diseases - surgery Ovarian Neoplasms - pathology Ovarian Neoplasms - surgery Testosterone - blood Tomography, X-Ray Computed Virilism - diagnosis |
title | Bilateral Mucinous Cystadenomas and Massive Edema of the Ovaries in a Virilized Adolescent Girl |
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