Oxygen Regulates Amino Acid Turnover and Carbohydrate Uptake During the Preimplantation Period of Mouse Embryo Development

Oxygen is a powerful regulator of preimplantation embryo development, affecting gene expression, the proteome, and energy metabolism. Even a transient exposure to atmospheric oxygen can have a negative impact on embryo development, which is greatest prior to compaction, and subsequent postcompaction...

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Veröffentlicht in:	Biology of reproduction 2012-07, Vol.87 (1), p.24, 1-24
Hauptverfasser:	WALE, Petra L, GARDENER, David K
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism Animals Biological and medical sciences Blastocyst - drug effects Blastocyst - metabolism Carbohydrate Metabolism Cleavage Stage, Ovum - drug effects Cleavage Stage, Ovum - metabolism Embryo Culture Techniques Embryonic Development - drug effects Embryonic Development - physiology Female Fertilization in Vitro - adverse effects Fertilization in Vitro - methods Fundamental and applied biological sciences. Psychology Humans Mice Mice, Inbred C57BL Mice, Inbred CBA Models, Animal Oxygen - administration & dosage Oxygen - metabolism Pregnancy Vertebrates: reproduction
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