Dopaminergic activity coincides with stimulus detection by the frontal lobe

Graphical abstract Highlights ► We compared the response latency of cortical and dopaminergic neurons. ► Dopaminergic neurons activate when frontal lobe neurons detect sensory stimuli. ► Dopaminergic activity is closely associated with the outcome of perceptual decisions. ► Reward modulates the acti...

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Veröffentlicht in:	Neuroscience 2012-08, Vol.218, p.181-184
Hauptverfasser:	de Lafuente, V, Romo, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Decision Making - physiology decisions detection dopamine Dopamine - metabolism Dopaminergic Neurons - physiology Electrophysiology Frontal Lobe - metabolism Fundamental and applied biological sciences. Psychology Macaca mulatta Neurology Neurons - physiology perception Perception - physiology Reaction Time - physiology reward somatosensory Vertebrates: nervous system and sense organs
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Beschreibung
Zusammenfassung:	Graphical abstract Highlights ► We compared the response latency of cortical and dopaminergic neurons. ► Dopaminergic neurons activate when frontal lobe neurons detect sensory stimuli. ► Dopaminergic activity is closely associated with the outcome of perceptual decisions. ► Reward modulates the activity of midbrain dopaminergic, but not of cortical neurons.
ISSN:	0306-4522 1873-7544
DOI:	10.1016/j.neuroscience.2012.05.026