Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens
Aim: The aims of the study were to isolate anti‐H9N2 bacteria from Korean Kimchi isolates and to evaluate its performance in cell line, egg and in specific pathogen‐free (SPF) chickens. Methods and Results: Using Madin–Darby canine kidney (MDCK) cell line, 220 bacterial isolates were screened and th...
Gespeichert in:
| Veröffentlicht in: | Journal of applied microbiology 2012-07, Vol.113 (1), p.163-171 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 171 |
|---|---|
| container_issue | 1 |
| container_start_page | 163 |
| container_title | Journal of applied microbiology |
| container_volume | 113 |
| creator | Seo, B.J Rather, I.A Kumar, V.J.R Choi, U.H Moon, M.R Lim, J.H Park, Y.H |
| description | Aim: The aims of the study were to isolate anti‐H9N2 bacteria from Korean Kimchi isolates and to evaluate its performance in cell line, egg and in specific pathogen‐free (SPF) chickens. Methods and Results: Using Madin–Darby canine kidney (MDCK) cell line, 220 bacterial isolates were screened and the isolate YML003 was selected having pronounced antiviral activity against H9N2 virus. This isolate was identified as Leuconostoc mesenteroides by 16S rRNA gene sequencing. Anti‐H9N2 activity of the strain was also evaluated by hemagglutination assay. Leuconostoc mesenteroides YML003 was assessed for its survival in gastric juice and 5% bile acid and the antibiotic susceptibility. Both live and heat‐killed cells were selected for in vivo chicken feeding experiment. Body weight, immune index, serobiochemical parameters and splenic IFN‐γ production were assessed during selected intervals. Viral population in the trachea and cloacae were calculated by quantitative real‐time reverse transcriptase PCR (qRT‐PCR). Conclusions: Leuconostoc mesenteroides YML003 exhibited anti‐H9N2 activity both in in vitro cell line as well as in vivo SPF Chickens. Significance and Impact of the Study: This is a primary report on the anti‐H9N2 activity by a Leuconostoc strain. Amid the increasing reports of avian influenza virus occurrence resulting in severe losses to the poultry industry, prophylactic administration of such probiotic strains are highly significant. |
| doi_str_mv | 10.1111/j.1365-2672.2012.05326.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_1028035502</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1020833950</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4736-76549d60494ad666e61701550882a4cdb5c183e8bfed7664db8d4ec529e3bdd13</originalsourceid><addsrcrecordid>eNqNks9uEzEQxlcIREvhFcASQiqHDeO_u3vgUKUlAaXlAFXFyfJ6va3TjR3Wu2nKBR6BZ-RJ8CYhSJzwxSPPb74Za74kQRhGOJ438xGmgqdEZGREAJMRcErEaP0gOdwnHm5ilnLIyEHyJIQ5AKbAxePkgBDOckHZYfL9bKWaXnXWO-RrNDO99s6Hzmu0MMG4zrTeViagL-czAIpUQAotW19a31mN1LWyLnSo8Xe_fvxcqu7GXxs3JFZWOWRd3fTGfVPoeFpckNdoZds-xGekb6y-NS48TR7Vqgnm2e4-Si7fnX0eT9PZx8n78cks1SyjIs0EZ0UlgBVMVUIII3AGmHPIc6KYrkqucU5NXtamyoRgVZlXzGhOCkPLqsL0KDne6sbZv_YmdHJhgzZNo5zxfZAYSA40CpL_QSGntOAQ0Zf_oHPfty5-RGJGcZFxIQbq-Y7qy4Wp5LK1C9Xeyz9biMCrHaCCVk3dKqdt-MsJwMA37d5uuTvbmPt9HoMcXCHncli-HJYvB1fIjSvkWn44OR-iWJ9u623ozHpfr9pbKTKacXl1MZEMpnB1OhnL08i_2PK18lJdt3Gmy09RmUcnsYwRTn8D3oLBeg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1431975660</pqid></control><display><type>article</type><title>Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens</title><source>Oxford University Press Journals All Titles (1996-Current)</source><source>MEDLINE</source><source>Wiley Online Library Journals Frontfile Complete</source><creator>Seo, B.J ; Rather, I.A ; Kumar, V.J.R ; Choi, U.H ; Moon, M.R ; Lim, J.H ; Park, Y.H</creator><creatorcontrib>Seo, B.J ; Rather, I.A ; Kumar, V.J.R ; Choi, U.H ; Moon, M.R ; Lim, J.H ; Park, Y.H</creatorcontrib><description>Aim: The aims of the study were to isolate anti‐H9N2 bacteria from Korean Kimchi isolates and to evaluate its performance in cell line, egg and in specific pathogen‐free (SPF) chickens. Methods and Results: Using Madin–Darby canine kidney (MDCK) cell line, 220 bacterial isolates were screened and the isolate YML003 was selected having pronounced antiviral activity against H9N2 virus. This isolate was identified as Leuconostoc mesenteroides by 16S rRNA gene sequencing. Anti‐H9N2 activity of the strain was also evaluated by hemagglutination assay. Leuconostoc mesenteroides YML003 was assessed for its survival in gastric juice and 5% bile acid and the antibiotic susceptibility. Both live and heat‐killed cells were selected for in vivo chicken feeding experiment. Body weight, immune index, serobiochemical parameters and splenic IFN‐γ production were assessed during selected intervals. Viral population in the trachea and cloacae were calculated by quantitative real‐time reverse transcriptase PCR (qRT‐PCR). Conclusions: Leuconostoc mesenteroides YML003 exhibited anti‐H9N2 activity both in in vitro cell line as well as in vivo SPF Chickens. Significance and Impact of the Study: This is a primary report on the anti‐H9N2 activity by a Leuconostoc strain. Amid the increasing reports of avian influenza virus occurrence resulting in severe losses to the poultry industry, prophylactic administration of such probiotic strains are highly significant.</description><identifier>ISSN: 1364-5072</identifier><identifier>EISSN: 1365-2672</identifier><identifier>DOI: 10.1111/j.1365-2672.2012.05326.x</identifier><identifier>PMID: 22548634</identifier><identifier>CODEN: JAMIFK</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Animals ; antibiotic resistance ; antiviral activity ; antiviral properties ; Avian flu ; avian influenza ; Avian influenza virus ; bacteria ; bile acids ; Biological and medical sciences ; body weight ; Brassica - microbiology ; chicken probiotics ; chickens ; Chickens - virology ; Cloaca - virology ; Dogs ; eggs ; Fundamental and applied biological sciences. Psychology ; gastric juice ; Genes ; hemagglutination ; Hemagglutination Tests ; immunomodulating ; Influenza A virus ; Influenza A Virus, H9N2 Subtype - pathogenicity ; Influenza in Birds - prevention & control ; interferon-gamma ; Interferon-gamma - metabolism ; kidneys ; kimchi ; Leuconostoc ; Leuconostoc - genetics ; Leuconostoc - isolation & purification ; Leuconostoc mesenteroides ; low-pathogenic avian influenza (H9N2) virus ; Madin Darby Canine Kidney Cells ; Microbiology ; Ovum - virology ; Poultry ; poultry industry ; Probiotics ; Probiotics - pharmacology ; Reverse Transcriptase Polymerase Chain Reaction ; ribosomal RNA ; RNA, Ribosomal, 16S - genetics ; specific pathogen-free animals ; Specific Pathogen-Free Organisms ; Spleen - immunology ; Trachea - virology ; Vegetables - microbiology ; viruses</subject><ispartof>Journal of applied microbiology, 2012-07, Vol.113 (1), p.163-171</ispartof><rights>2012 The Authors. Journal of Applied Microbiology © 2012 The Society for Applied Microbiology</rights><rights>2015 INIST-CNRS</rights><rights>2012 The Authors. Journal of Applied Microbiology © 2012 The Society for Applied Microbiology.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4736-76549d60494ad666e61701550882a4cdb5c183e8bfed7664db8d4ec529e3bdd13</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2672.2012.05326.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2672.2012.05326.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26010550$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22548634$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Seo, B.J</creatorcontrib><creatorcontrib>Rather, I.A</creatorcontrib><creatorcontrib>Kumar, V.J.R</creatorcontrib><creatorcontrib>Choi, U.H</creatorcontrib><creatorcontrib>Moon, M.R</creatorcontrib><creatorcontrib>Lim, J.H</creatorcontrib><creatorcontrib>Park, Y.H</creatorcontrib><title>Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens</title><title>Journal of applied microbiology</title><addtitle>J Appl Microbiol</addtitle><description>Aim: The aims of the study were to isolate anti‐H9N2 bacteria from Korean Kimchi isolates and to evaluate its performance in cell line, egg and in specific pathogen‐free (SPF) chickens. Methods and Results: Using Madin–Darby canine kidney (MDCK) cell line, 220 bacterial isolates were screened and the isolate YML003 was selected having pronounced antiviral activity against H9N2 virus. This isolate was identified as Leuconostoc mesenteroides by 16S rRNA gene sequencing. Anti‐H9N2 activity of the strain was also evaluated by hemagglutination assay. Leuconostoc mesenteroides YML003 was assessed for its survival in gastric juice and 5% bile acid and the antibiotic susceptibility. Both live and heat‐killed cells were selected for in vivo chicken feeding experiment. Body weight, immune index, serobiochemical parameters and splenic IFN‐γ production were assessed during selected intervals. Viral population in the trachea and cloacae were calculated by quantitative real‐time reverse transcriptase PCR (qRT‐PCR). Conclusions: Leuconostoc mesenteroides YML003 exhibited anti‐H9N2 activity both in in vitro cell line as well as in vivo SPF Chickens. Significance and Impact of the Study: This is a primary report on the anti‐H9N2 activity by a Leuconostoc strain. Amid the increasing reports of avian influenza virus occurrence resulting in severe losses to the poultry industry, prophylactic administration of such probiotic strains are highly significant.</description><subject>Animals</subject><subject>antibiotic resistance</subject><subject>antiviral activity</subject><subject>antiviral properties</subject><subject>Avian flu</subject><subject>avian influenza</subject><subject>Avian influenza virus</subject><subject>bacteria</subject><subject>bile acids</subject><subject>Biological and medical sciences</subject><subject>body weight</subject><subject>Brassica - microbiology</subject><subject>chicken probiotics</subject><subject>chickens</subject><subject>Chickens - virology</subject><subject>Cloaca - virology</subject><subject>Dogs</subject><subject>eggs</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>gastric juice</subject><subject>Genes</subject><subject>hemagglutination</subject><subject>Hemagglutination Tests</subject><subject>immunomodulating</subject><subject>Influenza A virus</subject><subject>Influenza A Virus, H9N2 Subtype - pathogenicity</subject><subject>Influenza in Birds - prevention & control</subject><subject>interferon-gamma</subject><subject>Interferon-gamma - metabolism</subject><subject>kidneys</subject><subject>kimchi</subject><subject>Leuconostoc</subject><subject>Leuconostoc - genetics</subject><subject>Leuconostoc - isolation & purification</subject><subject>Leuconostoc mesenteroides</subject><subject>low-pathogenic avian influenza (H9N2) virus</subject><subject>Madin Darby Canine Kidney Cells</subject><subject>Microbiology</subject><subject>Ovum - virology</subject><subject>Poultry</subject><subject>poultry industry</subject><subject>Probiotics</subject><subject>Probiotics - pharmacology</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>ribosomal RNA</subject><subject>RNA, Ribosomal, 16S - genetics</subject><subject>specific pathogen-free animals</subject><subject>Specific Pathogen-Free Organisms</subject><subject>Spleen - immunology</subject><subject>Trachea - virology</subject><subject>Vegetables - microbiology</subject><subject>viruses</subject><issn>1364-5072</issn><issn>1365-2672</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNks9uEzEQxlcIREvhFcASQiqHDeO_u3vgUKUlAaXlAFXFyfJ6va3TjR3Wu2nKBR6BZ-RJ8CYhSJzwxSPPb74Za74kQRhGOJ438xGmgqdEZGREAJMRcErEaP0gOdwnHm5ilnLIyEHyJIQ5AKbAxePkgBDOckHZYfL9bKWaXnXWO-RrNDO99s6Hzmu0MMG4zrTeViagL-czAIpUQAotW19a31mN1LWyLnSo8Xe_fvxcqu7GXxs3JFZWOWRd3fTGfVPoeFpckNdoZds-xGekb6y-NS48TR7Vqgnm2e4-Si7fnX0eT9PZx8n78cks1SyjIs0EZ0UlgBVMVUIII3AGmHPIc6KYrkqucU5NXtamyoRgVZlXzGhOCkPLqsL0KDne6sbZv_YmdHJhgzZNo5zxfZAYSA40CpL_QSGntOAQ0Zf_oHPfty5-RGJGcZFxIQbq-Y7qy4Wp5LK1C9Xeyz9biMCrHaCCVk3dKqdt-MsJwMA37d5uuTvbmPt9HoMcXCHncli-HJYvB1fIjSvkWn44OR-iWJ9u623ozHpfr9pbKTKacXl1MZEMpnB1OhnL08i_2PK18lJdt3Gmy09RmUcnsYwRTn8D3oLBeg</recordid><startdate>201207</startdate><enddate>201207</enddate><creator>Seo, B.J</creator><creator>Rather, I.A</creator><creator>Kumar, V.J.R</creator><creator>Choi, U.H</creator><creator>Moon, M.R</creator><creator>Lim, J.H</creator><creator>Park, Y.H</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><general>Oxford University Press</general><scope>FBQ</scope><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7QL</scope><scope>7QO</scope><scope>7T7</scope><scope>7TM</scope><scope>7U7</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>7U9</scope><scope>H94</scope></search><sort><creationdate>201207</creationdate><title>Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens</title><author>Seo, B.J ; Rather, I.A ; Kumar, V.J.R ; Choi, U.H ; Moon, M.R ; Lim, J.H ; Park, Y.H</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4736-76549d60494ad666e61701550882a4cdb5c183e8bfed7664db8d4ec529e3bdd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Animals</topic><topic>antibiotic resistance</topic><topic>antiviral activity</topic><topic>antiviral properties</topic><topic>Avian flu</topic><topic>avian influenza</topic><topic>Avian influenza virus</topic><topic>bacteria</topic><topic>bile acids</topic><topic>Biological and medical sciences</topic><topic>body weight</topic><topic>Brassica - microbiology</topic><topic>chicken probiotics</topic><topic>chickens</topic><topic>Chickens - virology</topic><topic>Cloaca - virology</topic><topic>Dogs</topic><topic>eggs</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>gastric juice</topic><topic>Genes</topic><topic>hemagglutination</topic><topic>Hemagglutination Tests</topic><topic>immunomodulating</topic><topic>Influenza A virus</topic><topic>Influenza A Virus, H9N2 Subtype - pathogenicity</topic><topic>Influenza in Birds - prevention & control</topic><topic>interferon-gamma</topic><topic>Interferon-gamma - metabolism</topic><topic>kidneys</topic><topic>kimchi</topic><topic>Leuconostoc</topic><topic>Leuconostoc - genetics</topic><topic>Leuconostoc - isolation & purification</topic><topic>Leuconostoc mesenteroides</topic><topic>low-pathogenic avian influenza (H9N2) virus</topic><topic>Madin Darby Canine Kidney Cells</topic><topic>Microbiology</topic><topic>Ovum - virology</topic><topic>Poultry</topic><topic>poultry industry</topic><topic>Probiotics</topic><topic>Probiotics - pharmacology</topic><topic>Reverse Transcriptase Polymerase Chain Reaction</topic><topic>ribosomal RNA</topic><topic>RNA, Ribosomal, 16S - genetics</topic><topic>specific pathogen-free animals</topic><topic>Specific Pathogen-Free Organisms</topic><topic>Spleen - immunology</topic><topic>Trachea - virology</topic><topic>Vegetables - microbiology</topic><topic>viruses</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Seo, B.J</creatorcontrib><creatorcontrib>Rather, I.A</creatorcontrib><creatorcontrib>Kumar, V.J.R</creatorcontrib><creatorcontrib>Choi, U.H</creatorcontrib><creatorcontrib>Moon, M.R</creatorcontrib><creatorcontrib>Lim, J.H</creatorcontrib><creatorcontrib>Park, Y.H</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><collection>MEDLINE - Academic</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>Journal of applied microbiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Seo, B.J</au><au>Rather, I.A</au><au>Kumar, V.J.R</au><au>Choi, U.H</au><au>Moon, M.R</au><au>Lim, J.H</au><au>Park, Y.H</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens</atitle><jtitle>Journal of applied microbiology</jtitle><addtitle>J Appl Microbiol</addtitle><date>2012-07</date><risdate>2012</risdate><volume>113</volume><issue>1</issue><spage>163</spage><epage>171</epage><pages>163-171</pages><issn>1364-5072</issn><eissn>1365-2672</eissn><coden>JAMIFK</coden><abstract>Aim: The aims of the study were to isolate anti‐H9N2 bacteria from Korean Kimchi isolates and to evaluate its performance in cell line, egg and in specific pathogen‐free (SPF) chickens. Methods and Results: Using Madin–Darby canine kidney (MDCK) cell line, 220 bacterial isolates were screened and the isolate YML003 was selected having pronounced antiviral activity against H9N2 virus. This isolate was identified as Leuconostoc mesenteroides by 16S rRNA gene sequencing. Anti‐H9N2 activity of the strain was also evaluated by hemagglutination assay. Leuconostoc mesenteroides YML003 was assessed for its survival in gastric juice and 5% bile acid and the antibiotic susceptibility. Both live and heat‐killed cells were selected for in vivo chicken feeding experiment. Body weight, immune index, serobiochemical parameters and splenic IFN‐γ production were assessed during selected intervals. Viral population in the trachea and cloacae were calculated by quantitative real‐time reverse transcriptase PCR (qRT‐PCR). Conclusions: Leuconostoc mesenteroides YML003 exhibited anti‐H9N2 activity both in in vitro cell line as well as in vivo SPF Chickens. Significance and Impact of the Study: This is a primary report on the anti‐H9N2 activity by a Leuconostoc strain. Amid the increasing reports of avian influenza virus occurrence resulting in severe losses to the poultry industry, prophylactic administration of such probiotic strains are highly significant.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>22548634</pmid><doi>10.1111/j.1365-2672.2012.05326.x</doi><tpages>9</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1364-5072 |
| ispartof | Journal of applied microbiology, 2012-07, Vol.113 (1), p.163-171 |
| issn | 1364-5072 1365-2672 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1028035502 |
| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Animals antibiotic resistance antiviral activity antiviral properties Avian flu avian influenza Avian influenza virus bacteria bile acids Biological and medical sciences body weight Brassica - microbiology chicken probiotics chickens Chickens - virology Cloaca - virology Dogs eggs Fundamental and applied biological sciences. Psychology gastric juice Genes hemagglutination Hemagglutination Tests immunomodulating Influenza A virus Influenza A Virus, H9N2 Subtype - pathogenicity Influenza in Birds - prevention & control interferon-gamma Interferon-gamma - metabolism kidneys kimchi Leuconostoc Leuconostoc - genetics Leuconostoc - isolation & purification Leuconostoc mesenteroides low-pathogenic avian influenza (H9N2) virus Madin Darby Canine Kidney Cells Microbiology Ovum - virology Poultry poultry industry Probiotics Probiotics - pharmacology Reverse Transcriptase Polymerase Chain Reaction ribosomal RNA RNA, Ribosomal, 16S - genetics specific pathogen-free animals Specific Pathogen-Free Organisms Spleen - immunology Trachea - virology Vegetables - microbiology viruses |
| title | Evaluation of Leuconostoc mesenteroides YML003 as a probiotic against low‐pathogenic avian influenza (H9N2) virus in chickens |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-08T06%3A38%3A17IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Evaluation%20of%20Leuconostoc%20mesenteroides%20YML003%20as%20a%20probiotic%20against%20low%E2%80%90pathogenic%20avian%20influenza%20(H9N2)%20virus%20in%20chickens&rft.jtitle=Journal%20of%20applied%20microbiology&rft.au=Seo,%20B.J&rft.date=2012-07&rft.volume=113&rft.issue=1&rft.spage=163&rft.epage=171&rft.pages=163-171&rft.issn=1364-5072&rft.eissn=1365-2672&rft.coden=JAMIFK&rft_id=info:doi/10.1111/j.1365-2672.2012.05326.x&rft_dat=%3Cproquest_pubme%3E1020833950%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1431975660&rft_id=info:pmid/22548634&rfr_iscdi=true |