Correlation of breast cancer susceptibility loci with patient characteristics, metastasis-free survival, and mRNA expression of the nearest genes

To understand the biology of low-risk breast cancer alleles, and to investigate whether these loci also contribute to disease progression that was once established, we examined the association of SNPs tagging the low-risk breast cancer loci in or near FGFR2 , LSP1 , MAP3K1, H19 , TOX3 , POU5F1P1 , M...

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Veröffentlicht in:	Breast cancer research and treatment 2012-06, Vol.133 (3), p.843-851
Hauptverfasser:	Riaz, Muhammad, Berns, Els M. J. J., Sieuwerts, Anieta M., Ruigrok-Ritstier, Kirsten, de Weerd, Vanja, Groenewoud, Arwin, Uitterlinden, Andrè G., Look, Maxime P., Klijn, Jan G. M., Sleijfer, Stefan, Foekens, John A., Martens, John W. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants Adult Aged Aged, 80 and over Alleles Analysis Biological and medical sciences Breast cancer Breast Neoplasms - genetics Breast Neoplasms - mortality Breast Neoplasms - pathology Cancer patients Cancer research Cancer therapies Development and progression Disease susceptibility Disease-Free Survival DNA Female Fibroblast growth factor receptor 2 Gene expression Gene Frequency Genes Genetic Loci Genetic Predisposition to Disease Genetic research Genotype Genotypes Gynecology. Andrology. Obstetrics Humans Mammary gland diseases Medical prognosis Medical sciences Medicine Medicine & Public Health Messenger RNA Metastasis Middle Aged Myc protein Neoplasm Metastasis Oncology Patient outcomes Polymorphism, Single Nucleotide Preclinical Study Prognosis Ribonucleic acid Risk factors Risk groups RNA Single-nucleotide polymorphism Survival Transcription, Genetic Tumor suppressor genes Tumors Young Adult
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