Biologically active, magnICON®-expressed EPO-Fc from stably transformed Nicotiana benthamiana plants presenting tetra-antennary N-glycan structures

► EPO-Fc was transiently expressed in Nicotiana benthamiana plants with humanized N-glycosylation. ► Plant-expressed EPO was shown to be active in vitro. ► N-glycan analysis of EPO-Fc revealed the presence of multi-antennary N-glycans. In the past two decades plants have emerged as a valuable altern...

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Veröffentlicht in:Journal of biotechnology 2012-08, Vol.160 (3-4), p.242-250
Hauptverfasser: Nagels, Bieke, Van Damme, Els J.M., Callewaert, Nico, Zabeau, Lennart, Tavernier, Jan, Delanghe, Joris R., Boets, Annemie, Castilho, Alexandra, Weterings, Koen
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