Inducible Prrxl1-CreER(T2) recombination activity in the somatosensory afferent pathway

Prrxl1-CreER(T2) transgenic mice expressing tamoxifen-inducible Cre recombinase were generated by modifying a Prrxl1-containing BAC clone. Cre recombination activity was examined in Prrxl1-CreER(T2); Rosa26 reporter mice at various embryonic and postnatal stages. Pregnant mice were treated with a si...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2012-07, Vol.50 (7), p.552-560
Hauptverfasser:	Hu, Ze-Lan, Huang, Ying, Tao, Xiao-Rong, Qi, Zheng-Han, Chen, Jia-Yin, Ding, Yu-Qiang
Format:	Artikel
Sprache:	eng
Schlagworte:	Afferent Pathways - embryology Afferent Pathways - physiology Animals Chromosomes, Artificial, Bacterial Embryo, Mammalian Female Founder Effect Gene Expression Regulation, Developmental - drug effects Genes, Reporter Homeodomain Proteins - genetics Integrases - genetics Mice Mice, Transgenic Nerve Tissue Proteins - genetics Pregnancy Promoter Regions, Genetic Proteins - genetics Recombination, Genetic - drug effects RNA, Untranslated Somatosensory Cortex - embryology Somatosensory Cortex - physiology Spinal Nerve Roots - embryology Spinal Nerve Roots - physiology Tamoxifen - administration & dosage Time Factors Transcription Factors - genetics Trigeminal Ganglion - embryology Trigeminal Ganglion - physiology
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