Dopamine D1 receptors regulate type 1 inositol 1,4,5-trisphosphate receptor expression via both AP-1- and NFATc4-mediated transcriptional processes

J. Neurochem. (2012) 122, 702–713. Although our recent report demonstrates the essential involvement of up‐regulation of a regulator of intracellular Ca2+ concentration, type 1 inositol 1,4,5‐trisphosphate receptors (IP3Rs‐1), mediated via dopamine D1‐like receptor (D1DR) stimulation in the cocaine‐...

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Veröffentlicht in:	Journal of neurochemistry 2012-08, Vol.122 (4), p.702-713
Hauptverfasser:	Mizuno, Koji, Kurokawa, Kazuhiro, Ohkuma, Seitaro
Format:	Artikel
Sprache:	eng
Schlagworte:	2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - analogs & derivatives 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine - pharmacology 5-trisphosphate receptors Addictive behaviors Adult and adolescent clinical studies Animals AP-1 Biological and medical sciences Blotting, Western Calcineurin - metabolism Calcium Calcium Signaling - drug effects Calcium Signaling - physiology Carbazoles - pharmacology Cell Nucleus - drug effects Cell Nucleus - metabolism Cells, Cultured Cellular biology Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Cerebral Cortex - cytology Cerebral Cortex - metabolism Chromatin Immunoprecipitation Cyclic AMP - metabolism Dopamine Agonists - pharmacology dopamine D1 receptors Drug addiction Enzyme Inhibitors - pharmacology Fundamental and applied biological sciences. Psychology Gene expression Immunohistochemistry Inositol 1,4,5-Trisphosphate Receptors - biosynthesis Inositol 1,4,5-Trisphosphate Receptors - drug effects Medical sciences Mice Microscopy, Fluorescence Neurochemistry Neurons - metabolism NFATC Transcription Factors - physiology NFATc4 Proteins Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Pyrroles - pharmacology Receptors, Dopamine D1 - agonists Receptors, Dopamine D1 - physiology Signal transduction Signal Transduction - physiology transcription Transcription Factor AP-1 - physiology Transcription, Genetic - physiology type 1 inositol 1 type 1 inositol 1,4,5‐trisphosphate receptors Vertebrates: nervous system and sense organs
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