Human pluripotent stem cell-derived hepatocytes support complete replication of hepatitis C virus

Background & Aims Worldwide, about 180 million people are chronically infected with the hepatitis C virus (HCV). Current in vitro culture systems for HCV depend chiefly on human hepatoma cell lines. Although primary human hepatocytes support HCV infection in vitro , and immunodeficient mice repo...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of hepatology 2012-08, Vol.57 (2), p.246-251
Hauptverfasser:	Roelandt, Philip, Obeid, Susan, Paeshuyse, Jan, Vanhove, Jolien, Van Lommel, Alfons, Nahmias, Yaakov, Nevens, Frederik, Neyts, Johan, Verfaillie, Catherine M
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Differentiation Embryonic Stem Cells - cytology Gastroenterology and Hepatology Gastroenterology. Liver. Pancreas. Abdomen Hepacivirus - physiology Hepatitis C virus Hepatocytes - virology Human embryonic stem cells Humans Medical sciences Pluripotent Stem Cells - cytology Replication Virus Replication
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!