Decreased paraoxonase 1 (PON1) lactonase activity in hemodialyzed and renal transplanted patients. A novel cardiovascular biomarker in end-stage renal disease

Human paraoxonase-1 (PON1) has also been described as a lactonase. Decreased PON1 lactonase activity was found to be a predictor of cardiovascular disease. Homocysteine thiolactonase activity may prevent proteins from homocysteinylation and is thought to be a protective factor against the progressio...

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Veröffentlicht in:	Nephrology, dialysis, transplantation dialysis, transplantation, 2012-07, Vol.27 (7), p.2866-2872
Hauptverfasser:	SZTANEK, Ferenc, SERES, Ildikó, HARANGI, Mariann, LOCSEY, Lajos, PADRA, Janos, PARAGH, György J. R, ASZTALOS, László, PARAGH, György
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Aryldialkylphosphatase - blood Biological and medical sciences Biomarkers - blood Cardiovascular Diseases - diagnosis Cardiovascular Diseases - enzymology Cardiovascular Diseases - etiology Case-Control Studies Emergency and intensive care: renal failure. Dialysis management Enzyme-Linked Immunosorbent Assay Female Follow-Up Studies Humans Intensive care medicine Kidney Failure, Chronic - complications Kidney Failure, Chronic - enzymology Kidney Failure, Chronic - therapy Kidney Transplantation - adverse effects Male Medical sciences Middle Aged Prognosis Renal Dialysis - adverse effects Risk Factors Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the urinary system
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