Daptomycin Compared to Vancomycin for the Treatment of Osteomyelitis: A Single-Center, Retrospective Cohort Study

Abstract Background Osteomyelitis (OM) is a serious infection with high rates of recurrence. Vancomycin has been used for decades in the treatment of OM, but, despite adequate dosing, 30% to 50% of patients experience infection recurrence within 12 months. Daptomycin, a novel lipopetide antibiotic,...

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Veröffentlicht in:	Clinical therapeutics 2012-07, Vol.34 (7), p.1521-1527
Hauptverfasser:	Moenster, Ryan P., PharmD, Linneman, Travis W., PharmD, Finnegan, Patrick M., PharmD, McDonald, Jay R., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Antibiotics Bacterial arthritis and osteitis Bacterial diseases Biological and medical sciences Cohort Studies daptomycin Daptomycin - adverse effects Daptomycin - therapeutic use Disease Drug therapy FDA approval Follow-Up Studies Hospitals, Veterans Human bacterial diseases Humans Infectious diseases Internal Medicine long-term antibiotics Male Medical Education Medical sciences Middle Aged Mortality osteomyelitis Osteomyelitis - drug therapy Pharmacology. Drug treatments Recurrence Retrospective Studies Staphylococcus infections Treatment Outcome vancomycin Vancomycin - adverse effects Vancomycin - therapeutic use
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