Sleep complaints among adolescent outpatients with major depressive disorder

Abstract Objective The objective of our study was to examine the prevalence rates of different sleep complaints among adolescent outpatients with major depressive disorder (MDD). Further, we examined whether depressed adolescents with and without different sleep disturbances differ in terms of sever...

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Veröffentlicht in:Sleep medicine 2012-08, Vol.13 (7), p.816-823
Hauptverfasser: Urrila, Anna S, Karlsson, Linnea, Kiviruusu, Olli, Pelkonen, Mirjami, Strandholm, Thea, Marttunen, Mauri
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container_end_page 823
container_issue 7
container_start_page 816
container_title Sleep medicine
container_volume 13
creator Urrila, Anna S
Karlsson, Linnea
Kiviruusu, Olli
Pelkonen, Mirjami
Strandholm, Thea
Marttunen, Mauri
description Abstract Objective The objective of our study was to examine the prevalence rates of different sleep complaints among adolescent outpatients with major depressive disorder (MDD). Further, we examined whether depressed adolescents with and without different sleep disturbances differ in terms of severity of depression, the presence of comorbid psychiatric disorders, and the symptom profile of depression. Methods A total of 166 Finnish adolescent psychiatric outpatients (age 13–19; mean 16.5 years old; 17.5% boys) diagnosed with unipolar MDD (as defined by DSM-IV criteria) were included in the study. Their sleep complaints were assessed with self-rating scales and clinical research interviews. Results The prevalence rate of subjective sleep complaints in adolescents with MDD was high: 83% of the adolescents experienced significantly disturbed sleep. The most common types of sleep complaints were nonrestorative sleep (69%) and insomnia (51%). The presence of sleep disturbances was associated with severity of depression: Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI) total sum scores were highest in adolescents with multiple sleep disturbances and lowest in adolescents with no sleep problems. Adolescents with multiple sleep disturbances differed most from adolescents with no or minor sleep disturbances in terms of thoughts about death, suicidal thoughts, and anhedonia. Conclusions These findings suggest a close link between sleep disturbances and the severity of depression in adolescent outpatients with MDD. In particular, the link between sleep disturbances and thoughts about death and suicidal thoughts calls for attention to sleep problems among depressed adolescents in clinical settings.
doi_str_mv 10.1016/j.sleep.2012.04.012
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Further, we examined whether depressed adolescents with and without different sleep disturbances differ in terms of severity of depression, the presence of comorbid psychiatric disorders, and the symptom profile of depression. Methods A total of 166 Finnish adolescent psychiatric outpatients (age 13–19; mean 16.5 years old; 17.5% boys) diagnosed with unipolar MDD (as defined by DSM-IV criteria) were included in the study. Their sleep complaints were assessed with self-rating scales and clinical research interviews. Results The prevalence rate of subjective sleep complaints in adolescents with MDD was high: 83% of the adolescents experienced significantly disturbed sleep. The most common types of sleep complaints were nonrestorative sleep (69%) and insomnia (51%). The presence of sleep disturbances was associated with severity of depression: Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI) total sum scores were highest in adolescents with multiple sleep disturbances and lowest in adolescents with no sleep problems. Adolescents with multiple sleep disturbances differed most from adolescents with no or minor sleep disturbances in terms of thoughts about death, suicidal thoughts, and anhedonia. Conclusions These findings suggest a close link between sleep disturbances and the severity of depression in adolescent outpatients with MDD. In particular, the link between sleep disturbances and thoughts about death and suicidal thoughts calls for attention to sleep problems among depressed adolescents in clinical settings.</description><identifier>ISSN: 1389-9457</identifier><identifier>EISSN: 1878-5506</identifier><identifier>DOI: 10.1016/j.sleep.2012.04.012</identifier><identifier>PMID: 22705242</identifier><language>eng</language><publisher>Netherlands: Elsevier B.V</publisher><subject>Adolescent ; Depression ; Depressive Disorder, Major - complications ; Disorders of Excessive Somnolence - complications ; Disorders of Excessive Somnolence - epidemiology ; Female ; Finland - epidemiology ; Humans ; Hypersomnia ; Insomnia ; Male ; Neurology ; Prevalence ; Psychiatric Status Rating Scales ; Sex Factors ; Sleep ; Sleep complaint ; Sleep Disorders, Circadian Rhythm - complications ; Sleep Disorders, Circadian Rhythm - epidemiology ; Sleep Initiation and Maintenance Disorders - complications ; Sleep Initiation and Maintenance Disorders - epidemiology ; Sleep Medicine ; Sleep Wake Disorders - complications ; Sleep Wake Disorders - epidemiology ; Sleep–wake-rhythm disturbance ; Surveys and Questionnaires ; Young Adult</subject><ispartof>Sleep medicine, 2012-08, Vol.13 (7), p.816-823</ispartof><rights>Elsevier B.V.</rights><rights>2012 Elsevier B.V.</rights><rights>Copyright © 2012 Elsevier B.V. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c414t-dd2664265825c98d8e8557b0fa93d8d26406ee52fd07a8795563a31d1ada98b23</citedby><cites>FETCH-LOGICAL-c414t-dd2664265825c98d8e8557b0fa93d8d26406ee52fd07a8795563a31d1ada98b23</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.sleep.2012.04.012$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22705242$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Urrila, Anna S</creatorcontrib><creatorcontrib>Karlsson, Linnea</creatorcontrib><creatorcontrib>Kiviruusu, Olli</creatorcontrib><creatorcontrib>Pelkonen, Mirjami</creatorcontrib><creatorcontrib>Strandholm, Thea</creatorcontrib><creatorcontrib>Marttunen, Mauri</creatorcontrib><title>Sleep complaints among adolescent outpatients with major depressive disorder</title><title>Sleep medicine</title><addtitle>Sleep Med</addtitle><description>Abstract Objective The objective of our study was to examine the prevalence rates of different sleep complaints among adolescent outpatients with major depressive disorder (MDD). Further, we examined whether depressed adolescents with and without different sleep disturbances differ in terms of severity of depression, the presence of comorbid psychiatric disorders, and the symptom profile of depression. Methods A total of 166 Finnish adolescent psychiatric outpatients (age 13–19; mean 16.5 years old; 17.5% boys) diagnosed with unipolar MDD (as defined by DSM-IV criteria) were included in the study. Their sleep complaints were assessed with self-rating scales and clinical research interviews. Results The prevalence rate of subjective sleep complaints in adolescents with MDD was high: 83% of the adolescents experienced significantly disturbed sleep. The most common types of sleep complaints were nonrestorative sleep (69%) and insomnia (51%). The presence of sleep disturbances was associated with severity of depression: Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI) total sum scores were highest in adolescents with multiple sleep disturbances and lowest in adolescents with no sleep problems. Adolescents with multiple sleep disturbances differed most from adolescents with no or minor sleep disturbances in terms of thoughts about death, suicidal thoughts, and anhedonia. Conclusions These findings suggest a close link between sleep disturbances and the severity of depression in adolescent outpatients with MDD. In particular, the link between sleep disturbances and thoughts about death and suicidal thoughts calls for attention to sleep problems among depressed adolescents in clinical settings.</description><subject>Adolescent</subject><subject>Depression</subject><subject>Depressive Disorder, Major - complications</subject><subject>Disorders of Excessive Somnolence - complications</subject><subject>Disorders of Excessive Somnolence - epidemiology</subject><subject>Female</subject><subject>Finland - epidemiology</subject><subject>Humans</subject><subject>Hypersomnia</subject><subject>Insomnia</subject><subject>Male</subject><subject>Neurology</subject><subject>Prevalence</subject><subject>Psychiatric Status Rating Scales</subject><subject>Sex Factors</subject><subject>Sleep</subject><subject>Sleep complaint</subject><subject>Sleep Disorders, Circadian Rhythm - complications</subject><subject>Sleep Disorders, Circadian Rhythm - epidemiology</subject><subject>Sleep Initiation and Maintenance Disorders - complications</subject><subject>Sleep Initiation and Maintenance Disorders - epidemiology</subject><subject>Sleep Medicine</subject><subject>Sleep Wake Disorders - complications</subject><subject>Sleep Wake Disorders - epidemiology</subject><subject>Sleep–wake-rhythm disturbance</subject><subject>Surveys and Questionnaires</subject><subject>Young Adult</subject><issn>1389-9457</issn><issn>1878-5506</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFUU1LxDAUDKL4_QsE6dFLa5ImbXpQkMUvWPCweg7Z5K2mtk1NWsV_b-quHrx4msCbefMyg9AJwRnBpDivs9AA9BnFhGaYZRG20D4RpUg5x8V2fOeiSivGyz10EEKNMSmJYLtoj9ISc8roPpovph2Jdm3fKNsNIVGt654TZVwDQUM3JG4cejVYmIYfdnhJWlU7nxjoPYRg3yExNjhvwB-hnZVqAhxv8BA93Vw_zu7S-cPt_exqnmpG2JAaQ4uC0YILynUljADBebnEK1XlRsQhwwUApyuDSyXKivMiVzkxRBlViSXND9HZem_v3dsIYZCtjbc2jerAjUESHA0qjIWI1HxN1d6F4GEle29b5T8jSU4xylp-xyinGCVmMkJUnW4MxmUL5lfzk1skXKwJEL_5bsHLoGNCGoz1oAdpnP3H4PKPXje2s1o1r_AJoXaj72KCksgQNXIxNTkVSWgssWJ5_gWIKJm6</recordid><startdate>20120801</startdate><enddate>20120801</enddate><creator>Urrila, Anna S</creator><creator>Karlsson, Linnea</creator><creator>Kiviruusu, Olli</creator><creator>Pelkonen, Mirjami</creator><creator>Strandholm, Thea</creator><creator>Marttunen, Mauri</creator><general>Elsevier B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120801</creationdate><title>Sleep complaints among adolescent outpatients with major depressive disorder</title><author>Urrila, Anna S ; Karlsson, Linnea ; Kiviruusu, Olli ; Pelkonen, Mirjami ; Strandholm, Thea ; Marttunen, Mauri</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c414t-dd2664265825c98d8e8557b0fa93d8d26406ee52fd07a8795563a31d1ada98b23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adolescent</topic><topic>Depression</topic><topic>Depressive Disorder, Major - complications</topic><topic>Disorders of Excessive Somnolence - complications</topic><topic>Disorders of Excessive Somnolence - epidemiology</topic><topic>Female</topic><topic>Finland - epidemiology</topic><topic>Humans</topic><topic>Hypersomnia</topic><topic>Insomnia</topic><topic>Male</topic><topic>Neurology</topic><topic>Prevalence</topic><topic>Psychiatric Status Rating Scales</topic><topic>Sex Factors</topic><topic>Sleep</topic><topic>Sleep complaint</topic><topic>Sleep Disorders, Circadian Rhythm - complications</topic><topic>Sleep Disorders, Circadian Rhythm - epidemiology</topic><topic>Sleep Initiation and Maintenance Disorders - complications</topic><topic>Sleep Initiation and Maintenance Disorders - epidemiology</topic><topic>Sleep Medicine</topic><topic>Sleep Wake Disorders - complications</topic><topic>Sleep Wake Disorders - epidemiology</topic><topic>Sleep–wake-rhythm disturbance</topic><topic>Surveys and Questionnaires</topic><topic>Young Adult</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Urrila, Anna S</creatorcontrib><creatorcontrib>Karlsson, Linnea</creatorcontrib><creatorcontrib>Kiviruusu, Olli</creatorcontrib><creatorcontrib>Pelkonen, Mirjami</creatorcontrib><creatorcontrib>Strandholm, Thea</creatorcontrib><creatorcontrib>Marttunen, Mauri</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Sleep medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Urrila, Anna S</au><au>Karlsson, Linnea</au><au>Kiviruusu, Olli</au><au>Pelkonen, Mirjami</au><au>Strandholm, Thea</au><au>Marttunen, Mauri</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Sleep complaints among adolescent outpatients with major depressive disorder</atitle><jtitle>Sleep medicine</jtitle><addtitle>Sleep Med</addtitle><date>2012-08-01</date><risdate>2012</risdate><volume>13</volume><issue>7</issue><spage>816</spage><epage>823</epage><pages>816-823</pages><issn>1389-9457</issn><eissn>1878-5506</eissn><abstract>Abstract Objective The objective of our study was to examine the prevalence rates of different sleep complaints among adolescent outpatients with major depressive disorder (MDD). Further, we examined whether depressed adolescents with and without different sleep disturbances differ in terms of severity of depression, the presence of comorbid psychiatric disorders, and the symptom profile of depression. Methods A total of 166 Finnish adolescent psychiatric outpatients (age 13–19; mean 16.5 years old; 17.5% boys) diagnosed with unipolar MDD (as defined by DSM-IV criteria) were included in the study. Their sleep complaints were assessed with self-rating scales and clinical research interviews. Results The prevalence rate of subjective sleep complaints in adolescents with MDD was high: 83% of the adolescents experienced significantly disturbed sleep. The most common types of sleep complaints were nonrestorative sleep (69%) and insomnia (51%). The presence of sleep disturbances was associated with severity of depression: Hamilton Depression Rating Scale (HDRS) and Beck Depression Inventory (BDI) total sum scores were highest in adolescents with multiple sleep disturbances and lowest in adolescents with no sleep problems. Adolescents with multiple sleep disturbances differed most from adolescents with no or minor sleep disturbances in terms of thoughts about death, suicidal thoughts, and anhedonia. Conclusions These findings suggest a close link between sleep disturbances and the severity of depression in adolescent outpatients with MDD. In particular, the link between sleep disturbances and thoughts about death and suicidal thoughts calls for attention to sleep problems among depressed adolescents in clinical settings.</abstract><cop>Netherlands</cop><pub>Elsevier B.V</pub><pmid>22705242</pmid><doi>10.1016/j.sleep.2012.04.012</doi><tpages>8</tpages></addata></record>
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subjects Adolescent
Depression
Depressive Disorder, Major - complications
Disorders of Excessive Somnolence - complications
Disorders of Excessive Somnolence - epidemiology
Female
Finland - epidemiology
Humans
Hypersomnia
Insomnia
Male
Neurology
Prevalence
Psychiatric Status Rating Scales
Sex Factors
Sleep
Sleep complaint
Sleep Disorders, Circadian Rhythm - complications
Sleep Disorders, Circadian Rhythm - epidemiology
Sleep Initiation and Maintenance Disorders - complications
Sleep Initiation and Maintenance Disorders - epidemiology
Sleep Medicine
Sleep Wake Disorders - complications
Sleep Wake Disorders - epidemiology
Sleep–wake-rhythm disturbance
Surveys and Questionnaires
Young Adult
title Sleep complaints among adolescent outpatients with major depressive disorder
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