Safety and Efficacy of Endovascular Therapy With a Simple Homemade Carbon Dioxide Delivery System in Patients With Ileofemoral Artery Diseases

Background: Carbon dioxide (CO2) has been used as an arterial contrast agent for high-risk patients who were allergic to iodinated contrast material and for those with chronic kidney disease (CKD). The feasibility, safety, imaging quality and therapeutic role of CO2 angiography in the endovascular t...

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Veröffentlicht in:Circulation Journal 2012, Vol.76(7), pp.1722-1728
Hauptverfasser: Kawasaki, Daizo, Fujii, Kenichi, Fukunaga, Masashi, Masutani, Motomaru, Nakata, Aya, Masuyama, Tohru
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container_end_page 1728
container_issue 7
container_start_page 1722
container_title Circulation Journal
container_volume 76
creator Kawasaki, Daizo
Fujii, Kenichi
Fukunaga, Masashi
Masutani, Motomaru
Nakata, Aya
Masuyama, Tohru
description Background: Carbon dioxide (CO2) has been used as an arterial contrast agent for high-risk patients who were allergic to iodinated contrast material and for those with chronic kidney disease (CKD). The feasibility, safety, imaging quality and therapeutic role of CO2 angiography in the endovascular therapy (EVT) for patients with CKD was evaluated. Methods and Results: EVT was performed in 107 consecutive patients with iliofemoral artery disease (148 limbs; mean age, 73±9 years) who were admitted to our hospital from January 2010 to April 2011. Intravascular ultrasound (IVUS)-guided EVT with CO2 was applied for the treatment of 50 patients (70 limbs) with CKD (group 1). IVUS-guided EVT with iodinated contrast media was applied for the treatment of 57 patients (78 limbs) without CKD (group 2). CO2 was injected by hand using a simple homemade delivery system. The overall technical success was 100% in both groups without any major complication. Preprocedure and postprocedure ankle-brachial indices significantly improved in the both groups (0.93±0.11 vs. 0.59±0.19, P
doi_str_mv 10.1253/circj.CJ-11-1382
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The feasibility, safety, imaging quality and therapeutic role of CO2 angiography in the endovascular therapy (EVT) for patients with CKD was evaluated. Methods and Results: EVT was performed in 107 consecutive patients with iliofemoral artery disease (148 limbs; mean age, 73±9 years) who were admitted to our hospital from January 2010 to April 2011. Intravascular ultrasound (IVUS)-guided EVT with CO2 was applied for the treatment of 50 patients (70 limbs) with CKD (group 1). IVUS-guided EVT with iodinated contrast media was applied for the treatment of 57 patients (78 limbs) without CKD (group 2). CO2 was injected by hand using a simple homemade delivery system. The overall technical success was 100% in both groups without any major complication. Preprocedure and postprocedure ankle-brachial indices significantly improved in the both groups (0.93±0.11 vs. 0.59±0.19, P&lt;0.01; 0.95±0.13 vs. 0.62±0.22, P&lt;0.01, respectively). All of the CO2 arteriograms were good or acceptable imaging quality if assessed by 2 independent observers. 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The feasibility, safety, imaging quality and therapeutic role of CO2 angiography in the endovascular therapy (EVT) for patients with CKD was evaluated. Methods and Results: EVT was performed in 107 consecutive patients with iliofemoral artery disease (148 limbs; mean age, 73±9 years) who were admitted to our hospital from January 2010 to April 2011. Intravascular ultrasound (IVUS)-guided EVT with CO2 was applied for the treatment of 50 patients (70 limbs) with CKD (group 1). IVUS-guided EVT with iodinated contrast media was applied for the treatment of 57 patients (78 limbs) without CKD (group 2). CO2 was injected by hand using a simple homemade delivery system. The overall technical success was 100% in both groups without any major complication. Preprocedure and postprocedure ankle-brachial indices significantly improved in the both groups (0.93±0.11 vs. 0.59±0.19, P&lt;0.01; 0.95±0.13 vs. 0.62±0.22, P&lt;0.01, respectively). All of the CO2 arteriograms were good or acceptable imaging quality if assessed by 2 independent observers. Conclusions: CO2 arteriograms, using an inexpensive simple homemade delivery system, are feasible and safe in patients with CKD in the evaluation and for EVT of iliofemoral artery disease.  (Circ J 2012; 76: 1722–1728)</description><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Ankle Brachial Index</subject><subject>Carbon Dioxide - administration &amp; dosage</subject><subject>Carbon Dioxide - adverse effects</subject><subject>Carbon dioxide angiography</subject><subject>Chi-Square Distribution</subject><subject>Chronic Disease</subject><subject>Chronic kidney disease</subject><subject>Contrast Media - administration &amp; dosage</subject><subject>Contrast Media - adverse effects</subject><subject>Endovascular Procedures - adverse effects</subject><subject>Endovascular Procedures - instrumentation</subject><subject>Endovascular therapy</subject><subject>Equipment Design</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Femoral Artery - diagnostic imaging</subject><subject>Glomerular Filtration Rate</subject><subject>Humans</subject><subject>Iliac Artery - diagnostic imaging</subject><subject>Injections</subject><subject>Japan</subject><subject>Kidney Diseases - complications</subject><subject>Kidney Diseases - physiopathology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Observer Variation</subject><subject>Peripheral Arterial Disease - complications</subject><subject>Peripheral Arterial Disease - diagnostic imaging</subject><subject>Peripheral Arterial Disease - therapy</subject><subject>Predictive Value of Tests</subject><subject>Radiography, Interventional - adverse effects</subject><subject>Radiography, Interventional - instrumentation</subject><subject>Reproducibility of Results</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><subject>Ultrasonography, Interventional</subject><issn>1346-9843</issn><issn>1347-4820</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkU1v1DAQhiMEoqVw54R85JLir8TJscpuaatKIG0RR2vWGbNeOfFieyvyJ_jNZLtLe5kP6ZnnMG9RfGT0kvFKfDEumu1ld1cyVjLR8FfFORNSlbLh9PXTXJdtI8VZ8S6lLaW8pVX7tjjjvKKS8fq8-LsCi3kiMPZkaa0zYCYSLFmOfXiEZPYeInnYYITdRH66vCFAVm7YeSQ3YcABeiQdxHUYycKFP25eF-jdI8aJrKaUcSBuJN8hOxxzOhpuPQaLQ4jgyVXMB3ThEkLC9L54Y8En_HDqF8WP6-VDd1Pef_t6213dl0a2MpeCK2taJUW_Rs5bVZu6bwzSplLITF2D6ampsOlB1YIjNcAMUIlqbWytmlZcFJ-P3l0Mv_eYsh5cMug9jBj2STPKZStUxdWM0iNqYkgpotW76AaI0wzpQwr6KQXd3WnG9CGF-eTTyb5fD9g_H_x_-wxcH4FtyvALnwGI2RmPJ6OqtTqUF_MLsIGocRT_AJhmn5E</recordid><startdate>2012</startdate><enddate>2012</enddate><creator>Kawasaki, Daizo</creator><creator>Fujii, Kenichi</creator><creator>Fukunaga, Masashi</creator><creator>Masutani, Motomaru</creator><creator>Nakata, Aya</creator><creator>Masuyama, Tohru</creator><general>The Japanese Circulation Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>2012</creationdate><title>Safety and Efficacy of Endovascular Therapy With a Simple Homemade Carbon Dioxide Delivery System in Patients With Ileofemoral Artery Diseases</title><author>Kawasaki, Daizo ; Fujii, Kenichi ; Fukunaga, Masashi ; Masutani, Motomaru ; Nakata, Aya ; Masuyama, Tohru</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c494t-327fc9743dbe22976c6d8ce0857e1c66acd0c5e8da7632e0ca1ca04e7bcf67893</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Ankle Brachial Index</topic><topic>Carbon Dioxide - administration &amp; dosage</topic><topic>Carbon Dioxide - adverse effects</topic><topic>Carbon dioxide angiography</topic><topic>Chi-Square Distribution</topic><topic>Chronic Disease</topic><topic>Chronic kidney disease</topic><topic>Contrast Media - administration &amp; dosage</topic><topic>Contrast Media - adverse effects</topic><topic>Endovascular Procedures - adverse effects</topic><topic>Endovascular Procedures - instrumentation</topic><topic>Endovascular therapy</topic><topic>Equipment Design</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Femoral Artery - diagnostic imaging</topic><topic>Glomerular Filtration Rate</topic><topic>Humans</topic><topic>Iliac Artery - diagnostic imaging</topic><topic>Injections</topic><topic>Japan</topic><topic>Kidney Diseases - complications</topic><topic>Kidney Diseases - physiopathology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Observer Variation</topic><topic>Peripheral Arterial Disease - complications</topic><topic>Peripheral Arterial Disease - diagnostic imaging</topic><topic>Peripheral Arterial Disease - therapy</topic><topic>Predictive Value of Tests</topic><topic>Radiography, Interventional - adverse effects</topic><topic>Radiography, Interventional - instrumentation</topic><topic>Reproducibility of Results</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><topic>Ultrasonography, Interventional</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kawasaki, Daizo</creatorcontrib><creatorcontrib>Fujii, Kenichi</creatorcontrib><creatorcontrib>Fukunaga, Masashi</creatorcontrib><creatorcontrib>Masutani, Motomaru</creatorcontrib><creatorcontrib>Nakata, Aya</creatorcontrib><creatorcontrib>Masuyama, Tohru</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation Journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kawasaki, Daizo</au><au>Fujii, Kenichi</au><au>Fukunaga, Masashi</au><au>Masutani, Motomaru</au><au>Nakata, Aya</au><au>Masuyama, Tohru</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Safety and Efficacy of Endovascular Therapy With a Simple Homemade Carbon Dioxide Delivery System in Patients With Ileofemoral Artery Diseases</atitle><jtitle>Circulation Journal</jtitle><addtitle>Circ J</addtitle><date>2012</date><risdate>2012</risdate><volume>76</volume><issue>7</issue><spage>1722</spage><epage>1728</epage><pages>1722-1728</pages><issn>1346-9843</issn><eissn>1347-4820</eissn><abstract>Background: Carbon dioxide (CO2) has been used as an arterial contrast agent for high-risk patients who were allergic to iodinated contrast material and for those with chronic kidney disease (CKD). The feasibility, safety, imaging quality and therapeutic role of CO2 angiography in the endovascular therapy (EVT) for patients with CKD was evaluated. Methods and Results: EVT was performed in 107 consecutive patients with iliofemoral artery disease (148 limbs; mean age, 73±9 years) who were admitted to our hospital from January 2010 to April 2011. Intravascular ultrasound (IVUS)-guided EVT with CO2 was applied for the treatment of 50 patients (70 limbs) with CKD (group 1). IVUS-guided EVT with iodinated contrast media was applied for the treatment of 57 patients (78 limbs) without CKD (group 2). CO2 was injected by hand using a simple homemade delivery system. The overall technical success was 100% in both groups without any major complication. Preprocedure and postprocedure ankle-brachial indices significantly improved in the both groups (0.93±0.11 vs. 0.59±0.19, P&lt;0.01; 0.95±0.13 vs. 0.62±0.22, P&lt;0.01, respectively). All of the CO2 arteriograms were good or acceptable imaging quality if assessed by 2 independent observers. Conclusions: CO2 arteriograms, using an inexpensive simple homemade delivery system, are feasible and safe in patients with CKD in the evaluation and for EVT of iliofemoral artery disease.  (Circ J 2012; 76: 1722–1728)</abstract><cop>Japan</cop><pub>The Japanese Circulation Society</pub><pmid>22504126</pmid><doi>10.1253/circj.CJ-11-1382</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record>
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subjects Aged
Aged, 80 and over
Ankle Brachial Index
Carbon Dioxide - administration & dosage
Carbon Dioxide - adverse effects
Carbon dioxide angiography
Chi-Square Distribution
Chronic Disease
Chronic kidney disease
Contrast Media - administration & dosage
Contrast Media - adverse effects
Endovascular Procedures - adverse effects
Endovascular Procedures - instrumentation
Endovascular therapy
Equipment Design
Feasibility Studies
Female
Femoral Artery - diagnostic imaging
Glomerular Filtration Rate
Humans
Iliac Artery - diagnostic imaging
Injections
Japan
Kidney Diseases - complications
Kidney Diseases - physiopathology
Male
Middle Aged
Observer Variation
Peripheral Arterial Disease - complications
Peripheral Arterial Disease - diagnostic imaging
Peripheral Arterial Disease - therapy
Predictive Value of Tests
Radiography, Interventional - adverse effects
Radiography, Interventional - instrumentation
Reproducibility of Results
Retrospective Studies
Treatment Outcome
Ultrasonography, Interventional
title Safety and Efficacy of Endovascular Therapy With a Simple Homemade Carbon Dioxide Delivery System in Patients With Ileofemoral Artery Diseases
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