Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome

The 8p11 myeloproliferative syndrome (EMS) is an aggressive neoplasm caused by the fusion of various partner genes to fibroblast growth factor receptor 1 (FGFR1). Various FGFR1 fusions are associated with subtly distinct disease phenotypes. Here, we report a new translocation at the FGFR1 locus in a...

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Veröffentlicht in:	Genes chromosomes & cancer 2012-09, Vol.51 (9), p.890-897
Hauptverfasser:	Li, Feng, Zhai, Yong-Ping, Tang, Yu-Mei, Wang, Li-Ping, Wan, Pin-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amino Acid Sequence Base Sequence Chromosomes, Human, Pair 1 - genetics Chromosomes, Human, Pair 8 - genetics Humans In Situ Hybridization, Fluorescence Male Molecular Sequence Data Myeloproliferative Disorders - genetics Nuclear Pore Complex Proteins - genetics Oncogene Proteins, Fusion - genetics Prognosis Proto-Oncogene Proteins - genetics Real-Time Polymerase Chain Reaction Receptor, Fibroblast Growth Factor, Type 1 - genetics Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - genetics Translocation, Genetic - genetics
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