Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: Case report and review of the literature
Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is well recognized and there are concerns that this may also be true for inflammatory bowel disease patients....
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| Veröffentlicht in: | Journal of Crohn's and colitis 2012-08, Vol.6 (7), p.792-795 |
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| container_issue | 7 |
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| container_title | Journal of Crohn's and colitis |
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| creator | Vilas-Boas, Filipe Magro, Fernando Balhau, Rui Lopes, José M. Beça, Francisco Eloy, Catarina Lopes, Susana Macedo, Guilherme |
| description | Thiopurines are widely used for remission maintenance and post-operative recurrence prevention in Crohn's disease. The increased risk of cancer in transplant recipients on azathioprine is well recognized and there are concerns that this may also be true for inflammatory bowel disease patients.
We report a case of a 33-year-old Caucasian woman with Crohn's disease treated with azathioprine for 9years who developed an ulcerated lesion at the right superior retromolar trigone. Biopsy specimen revealed a squamous cell carcinoma. |
| doi_str_mv | 10.1016/j.crohns.2012.03.004 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1873-9946 |
| ispartof | Journal of Crohn's and colitis, 2012-08, Vol.6 (7), p.792-795 |
| issn | 1873-9946 1876-4479 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1024352704 |
| source | MEDLINE; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Adult Azathioprine Azathioprine - adverse effects Carcinoma, Squamous Cell - chemically induced Crohn Disease - drug therapy Crohn's disease Female Humans Immunosuppressive Agents - adverse effects Mouth Neoplasms - chemically induced Oral cancer Thiopurines |
| title | Oral squamous cell carcinoma in a Crohn's disease patient taking azathioprine: Case report and review of the literature |
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