CXCR4/SDF-1α-mediated chemotaxis in an in vivo model of metastatic esophageal carcinoma

The chemokine receptor CXCR4 and its ligand (stromal cell-derived factor-1alpha; SDF-1α) play an important role in tumor cell chemotaxis and metastatic homing of esophageal carcinoma. Several methods are available to examine tumor cell migration in vitro. However, in vivo chemotaxis is subject to co...

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Veröffentlicht in:	In vivo (Athens) 2012-07, Vol.26 (4), p.711-718
Hauptverfasser:	Gros, Stephanie J, Graeff, Hanna, Drenckhan, Astrid, Kurschat, Nina, Blessmann, Marco, Rawnaq, Tamina, Izbicki, Jakob R
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Chemokine CXCL12 - physiology Chemotaxis - physiology Esophageal Neoplasms - pathology Mice Neoplasm Metastasis Receptors, CXCR4 - physiology
Online-Zugang:	Volltext
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