Tumor-educated macrophages promote tumor growth and peritoneal metastasis in an orthotopic nude mouse model of human pancreatic cancer

Macrophages promote tumor growth by stimulating tumor-associated angiogenesis, cancer-cell invasion, migration, intravasation, and suppression of antitumor immune responses. Ten transgenic nude mice, ubiquitously expressing green fluorescent protein (GFP), were injected subcutaneously with the human...

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Veröffentlicht in:In vivo (Athens) 2012-07, Vol.26 (4), p.565-569
Hauptverfasser: Menen, Rhiana S, Hassanein, Mohamed K, Momiyama, Masashi, Suetsugu, Atsushi, Moossa, Abdool R, Hoffman, Robert M, Bouvet, Michael
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Sprache:eng
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