Adsorption of Enamel Matrix Proteins to a Bovine‐Derived Bone Grafting Material and Its Regulation of Cell Adhesion, Proliferation, and Differentiation

Background: The use of various combinations of enamel matrix derivative (EMD) and grafting materials has been shown to promote periodontal wound healing/regeneration. However, the downstream cellular behavior of periodontal ligament (PDL) cells and osteoblasts has not yet been studied. Furthermore,...

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Veröffentlicht in:	Journal of periodontology (1970) 2012-07, Vol.83 (7), p.936-947
Hauptverfasser:	Miron, Richard J., D. Bosshardt, Dieter, Hedbom, Erik, Zhang, Yufeng, Haenni, Beat, Buser, Daniel, Sculean, Anton
Format:	Artikel
Sprache:	eng
Schlagworte:	Adsorption Alkaline Phosphatase - analysis Animals Anthraquinones Biocompatible materials Biological and medical sciences Blood blood proteins Bone Morphogenetic Protein 2 - analysis bone regeneration Bone Substitutes - chemistry Calcification, Physiologic - drug effects Cattle Cell Adhesion - drug effects Cell Culture Techniques Cell Differentiation - drug effects Cell differentiation, maturation, development, hematopoiesis Cell physiology Cell Proliferation - drug effects Coated Materials, Biocompatible - chemistry Coated Materials, Biocompatible - pharmacology Collagen Type I - analysis Coloring Agents Core Binding Factor Alpha 1 Subunit - analysis Dental Enamel Proteins - chemistry Dental Enamel Proteins - pharmacology Dentistry enamel matrix proteins Fluorescent Dyes Fundamental and applied biological sciences. Psychology guided tissue regeneration Humans Medical sciences Microscopy, Electron, Scanning Minerals - chemistry Molecular and cellular biology Osteoblasts - drug effects Osteoblasts - physiology Osteocalcin - analysis Otorhinolaryngology. Stomatology periodontal Periodontal Ligament - cytology Periodontal Ligament - drug effects Real-Time Polymerase Chain Reaction tissue engineering Transforming Growth Factor beta1 - analysis
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