Facile and efficient synthesis of quinolin-2(1H)-ones via cyclization of penta-2,4-dienamides mediated by H2SO4
A facile and efficient synthesis of substituted quinolin-2(1H)-ones is developed via intramolecular cyclization of penta-2,4-dienamides mediated by concentrated H(2)SO(4) (98%), and a mechanism involving the formation of a dicationic superelectrophile, and subsequent intramolecular nucleophilic cycl...
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| Veröffentlicht in: | Organic & biomolecular chemistry 2012-08, Vol.10 (29), p.5643-5646 |
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| container_end_page | 5646 |
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| container_issue | 29 |
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| container_title | Organic & biomolecular chemistry |
| container_volume | 10 |
| creator | Liu, Xu Xin, Xin Xiang, Dexuan Zhang, Rui Kumar, Santosh Zhou, Fenguo Dong, Dewen |
| description | A facile and efficient synthesis of substituted quinolin-2(1H)-ones is developed via intramolecular cyclization of penta-2,4-dienamides mediated by concentrated H(2)SO(4) (98%), and a mechanism involving the formation of a dicationic superelectrophile, and subsequent intramolecular nucleophilic cyclization reactions is proposed. |
| doi_str_mv | 10.1039/c2ob25767j |
| format | Article |
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| fulltext | fulltext |
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| ispartof | Organic & biomolecular chemistry, 2012-08, Vol.10 (29), p.5643-5646 |
| issn | 1477-0520 1477-0539 |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals 2008-; Alma/SFX Local Collection |
| subjects | Alkadienes - chemistry Amides - chemistry Cyclization Quinolones - chemical synthesis Quinolones - chemistry Stereoisomerism Sulfuric Acids - chemistry |
| title | Facile and efficient synthesis of quinolin-2(1H)-ones via cyclization of penta-2,4-dienamides mediated by H2SO4 |
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