Assessment of treatment response in patients with glioblastoma using O-(2-18F-fluoroethyl)-L-tyrosine PET in comparison to MRI

The assessment of treatment response in glioblastoma is difficult with MRI because reactive blood-brain barrier alterations with contrast enhancement can mimic tumor progression. In this study, we investigated the predictive value of PET using O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET PET) durin...

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Veröffentlicht in:	Journal of Nuclear Medicine 2012-07, Vol.53 (7), p.1048-1057
Hauptverfasser:	Galldiks, Norbert, Langen, Karl-Josef, Holy, Richard, Pinkawa, Michael, Stoffels, Gabriele, Nolte, Kay W, Kaiser, Hans J, Filss, Christan P, Fink, Gereon R, Coenen, Heinz H, Eble, Michael J, Piroth, Marc D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Amino acids Brain cancer Brain Neoplasms - diagnostic imaging Brain Neoplasms - therapy Chemoradiotherapy Contrast Media Disease Progression Disease-Free Survival Drug therapy Female Gadolinium Glioblastoma - diagnostic imaging Glioblastoma - therapy Humans Kaplan-Meier Estimate Magnetic Resonance Imaging Male Middle Aged Neurosurgical Procedures Positron-Emission Tomography Prognosis Proportional Hazards Models Prospective Studies Radiation therapy Radiopharmaceuticals Studies Survival Analysis Treatment Outcome Tumors Tyrosine - analogs & derivatives
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