Increased EZH2 protein expression is associated with invasive urothelial carcinoma of the bladder

Abstract Objectives Elevated polycomb group protein Enhancer of Zest Homolog 2 (EZH2) expression has been associated with progression to more advanced disease in a variety of malignancies. We examined EZH2 protein expression levels in bladder tissue specimens from patients with urothelial carcinoma...

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Veröffentlicht in:	Urologic oncology 2012-07, Vol.30 (4), p.428-433
Hauptverfasser:	Wang, Hang, Ph.D, Albadine, Roula, M.D, Magheli, Ahmed, M.D, Guzzo, Thomas J., M.D., M.P.H, Ball, Mark W., M.D, Hinz, Stefan, M.D, Schoenberg, Mark P., M.D, Netto, George J., M.D, Gonzalgo, Mark L., M.D., Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Biological and medical sciences Biomarkers, Tumor - biosynthesis Carcinoma, Transitional Cell - metabolism Carcinoma, Transitional Cell - pathology Carcinoma, Transitional Cell - surgery Cystectomy - methods Enhancer of Zeste Homolog 2 Protein EZH2 Female Humans Immunohistochemistry - statistics & numerical data Kaplan-Meier Estimate Male Medical sciences Middle Aged Neoplasm Grading Neoplasm Invasiveness Neoplasm Staging Nephrology. Urinary tract diseases Polycomb protein Polycomb Repressive Complex 2 - biosynthesis Proportional Hazards Models Tissue Array Analysis - statistics & numerical data Tissue microarray Tumors Tumors of the urinary system Urinary bladder cancer Urinary Bladder Neoplasms - metabolism Urinary Bladder Neoplasms - pathology Urinary Bladder Neoplasms - surgery Urinary tract. Prostate gland Urology Urothelial carcinoma
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