Lesion of medial prefrontal cortex reduces morphine-induced extracellular dopamine level in the ventral tegmental area: A microdialysis study in rats

Drug addiction is a chronic disorder characterized by compulsive drug-seeking behavior despite severe negative consequences. Most abused drugs increase dopamine release in the ventral tegmental area (VTA) and in the nucleus accumbens (NA). The medial prefrontal cortex (mPFC), a part of the mesocorti...

Ausführliche Beschreibung