Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block

Abstract Objectives We assessed the prevalence of true acute myocardial infarction and the need for emergent revascularization among patients with new or presumably new left bundle branch block (nLBBB) for whom the primary percutaneous coronary intervention protocol was activated. Methods and Result...

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Veröffentlicht in:Journal of electrocardiology 2012-07, Vol.45 (4), p.361-367
Hauptverfasser: Mehta, Nilay, DO, Huang, Henry D., MD, Bandeali, Salman, MD, Wilson, James M., MD, Birnbaum, Yochai, MD
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container_end_page 367
container_issue 4
container_start_page 361
container_title Journal of electrocardiology
container_volume 45
creator Mehta, Nilay, DO
Huang, Henry D., MD
Bandeali, Salman, MD
Wilson, James M., MD
Birnbaum, Yochai, MD
description Abstract Objectives We assessed the prevalence of true acute myocardial infarction and the need for emergent revascularization among patients with new or presumably new left bundle branch block (nLBBB) for whom the primary percutaneous coronary intervention protocol was activated. Methods and Results Among 802 patients, 69 (8.6%) had nLBBB. The chief presenting symptom was chest pain or cardiac arrest in 36 patients (52.2%) and shortness of breath in 15 (21.7%). Less than 30% of the patients had elevated cardiac troponin-I, and less than 10% had elevated creatine kinase–MB. Only 11.6% of the patients underwent emergent revascularization; the rate was higher for patients who presented with chest pain or cardiac arrest or shortness of breath than for patients who presented with other symptoms. Conclusions Acute myocardial infarction and the need for emergent revascularization are relatively uncommon among patients who present with nLBBB, especially when symptoms are atypical. Current guidelines for primary percutaneous coronary intervention protocol activation for nLBBB should be reconsidered.
doi_str_mv 10.1016/j.jelectrocard.2012.04.006
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Methods and Results Among 802 patients, 69 (8.6%) had nLBBB. The chief presenting symptom was chest pain or cardiac arrest in 36 patients (52.2%) and shortness of breath in 15 (21.7%). Less than 30% of the patients had elevated cardiac troponin-I, and less than 10% had elevated creatine kinase–MB. Only 11.6% of the patients underwent emergent revascularization; the rate was higher for patients who presented with chest pain or cardiac arrest or shortness of breath than for patients who presented with other symptoms. Conclusions Acute myocardial infarction and the need for emergent revascularization are relatively uncommon among patients who present with nLBBB, especially when symptoms are atypical. Current guidelines for primary percutaneous coronary intervention protocol activation for nLBBB should be reconsidered.</description><identifier>ISSN: 0022-0736</identifier><identifier>EISSN: 1532-8430</identifier><identifier>DOI: 10.1016/j.jelectrocard.2012.04.006</identifier><identifier>PMID: 22575807</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Acute myocardial infarction ; Aged ; Angioplasty, Balloon, Coronary ; Bundle-Branch Block - complications ; Bundle-Branch Block - diagnosis ; Bundle-Branch Block - therapy ; Cardiovascular ; Creatine Kinase, MB Form - blood ; Electrocardiogram ; Electrocardiography ; Emergencies ; Female ; Humans ; Left bundle branch block ; Male ; Myocardial Infarction - complications ; Myocardial Infarction - diagnosis ; Myocardial Infarction - therapy ; Primary percutaneous coronary intervention ; Troponin I - blood</subject><ispartof>Journal of electrocardiology, 2012-07, Vol.45 (4), p.361-367</ispartof><rights>Elsevier Inc.</rights><rights>2012 Elsevier Inc.</rights><rights>Copyright © 2012 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c435t-59a3053b18fbfff84fc001efdfdc4fb79f6a584b53f16cff5773007b2cb96bd13</citedby><cites>FETCH-LOGICAL-c435t-59a3053b18fbfff84fc001efdfdc4fb79f6a584b53f16cff5773007b2cb96bd13</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.jelectrocard.2012.04.006$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22575807$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mehta, Nilay, DO</creatorcontrib><creatorcontrib>Huang, Henry D., MD</creatorcontrib><creatorcontrib>Bandeali, Salman, MD</creatorcontrib><creatorcontrib>Wilson, James M., MD</creatorcontrib><creatorcontrib>Birnbaum, Yochai, MD</creatorcontrib><title>Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block</title><title>Journal of electrocardiology</title><addtitle>J Electrocardiol</addtitle><description>Abstract Objectives We assessed the prevalence of true acute myocardial infarction and the need for emergent revascularization among patients with new or presumably new left bundle branch block (nLBBB) for whom the primary percutaneous coronary intervention protocol was activated. Methods and Results Among 802 patients, 69 (8.6%) had nLBBB. The chief presenting symptom was chest pain or cardiac arrest in 36 patients (52.2%) and shortness of breath in 15 (21.7%). Less than 30% of the patients had elevated cardiac troponin-I, and less than 10% had elevated creatine kinase–MB. Only 11.6% of the patients underwent emergent revascularization; the rate was higher for patients who presented with chest pain or cardiac arrest or shortness of breath than for patients who presented with other symptoms. Conclusions Acute myocardial infarction and the need for emergent revascularization are relatively uncommon among patients who present with nLBBB, especially when symptoms are atypical. Current guidelines for primary percutaneous coronary intervention protocol activation for nLBBB should be reconsidered.</description><subject>Acute myocardial infarction</subject><subject>Aged</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Bundle-Branch Block - complications</subject><subject>Bundle-Branch Block - diagnosis</subject><subject>Bundle-Branch Block - therapy</subject><subject>Cardiovascular</subject><subject>Creatine Kinase, MB Form - blood</subject><subject>Electrocardiogram</subject><subject>Electrocardiography</subject><subject>Emergencies</subject><subject>Female</subject><subject>Humans</subject><subject>Left bundle branch block</subject><subject>Male</subject><subject>Myocardial Infarction - complications</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - therapy</subject><subject>Primary percutaneous coronary intervention</subject><subject>Troponin I - blood</subject><issn>0022-0736</issn><issn>1532-8430</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU1rFTEUhoMo9lr9CxJcuZnxJJlPF4K0fhQKFdR1SDInNNNM5prMtNx_34y3inQlBJLF876HPIeQNwxKBqx5N5YjejRLnI2KQ8mB8RKqEqB5QnasFrzoKgFPyQ6A8wJa0ZyQFymNANDzlj8nJ5zXbd1BuyP6W8Rb5TEYpLOlyqwL0unwu9kpT12wKprFzSE_6V4tDsOS6J1bruk-Ylonpf2BBryjHu1C9RoGj4WOKphrqv1sbl6SZ1b5hK8e7lPy8_OnH2dfi8urLxdnHy8LU4l6KepeCaiFZp3V1tqusgaAoR3sYCqr2942qu4qXQvLGmNt3bYCoNXc6L7RAxOn5O2xdx_nXyumRU4uGfReBZzXJBlw1nf59Bl9f0RNnFOKaOU-uknFQ4bk5liO8l_HcnMsoZLZcQ6_fpiz6gmHv9E_UjNwfgQw__bWYZTJuM3w4GKulMPs_m_Oh0c1xrvgjPI3eMA0zmsM2adkMuWM_L5te1s249kb7zpxD_Hnq0o</recordid><startdate>20120701</startdate><enddate>20120701</enddate><creator>Mehta, Nilay, DO</creator><creator>Huang, Henry D., MD</creator><creator>Bandeali, Salman, MD</creator><creator>Wilson, James M., MD</creator><creator>Birnbaum, Yochai, MD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120701</creationdate><title>Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block</title><author>Mehta, Nilay, DO ; Huang, Henry D., MD ; Bandeali, Salman, MD ; Wilson, James M., MD ; Birnbaum, Yochai, MD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-59a3053b18fbfff84fc001efdfdc4fb79f6a584b53f16cff5773007b2cb96bd13</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Acute myocardial infarction</topic><topic>Aged</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Bundle-Branch Block - complications</topic><topic>Bundle-Branch Block - diagnosis</topic><topic>Bundle-Branch Block - therapy</topic><topic>Cardiovascular</topic><topic>Creatine Kinase, MB Form - blood</topic><topic>Electrocardiogram</topic><topic>Electrocardiography</topic><topic>Emergencies</topic><topic>Female</topic><topic>Humans</topic><topic>Left bundle branch block</topic><topic>Male</topic><topic>Myocardial Infarction - complications</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - therapy</topic><topic>Primary percutaneous coronary intervention</topic><topic>Troponin I - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mehta, Nilay, DO</creatorcontrib><creatorcontrib>Huang, Henry D., MD</creatorcontrib><creatorcontrib>Bandeali, Salman, MD</creatorcontrib><creatorcontrib>Wilson, James M., MD</creatorcontrib><creatorcontrib>Birnbaum, Yochai, MD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of electrocardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mehta, Nilay, DO</au><au>Huang, Henry D., MD</au><au>Bandeali, Salman, MD</au><au>Wilson, James M., MD</au><au>Birnbaum, Yochai, MD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block</atitle><jtitle>Journal of electrocardiology</jtitle><addtitle>J Electrocardiol</addtitle><date>2012-07-01</date><risdate>2012</risdate><volume>45</volume><issue>4</issue><spage>361</spage><epage>367</epage><pages>361-367</pages><issn>0022-0736</issn><eissn>1532-8430</eissn><abstract>Abstract Objectives We assessed the prevalence of true acute myocardial infarction and the need for emergent revascularization among patients with new or presumably new left bundle branch block (nLBBB) for whom the primary percutaneous coronary intervention protocol was activated. Methods and Results Among 802 patients, 69 (8.6%) had nLBBB. The chief presenting symptom was chest pain or cardiac arrest in 36 patients (52.2%) and shortness of breath in 15 (21.7%). Less than 30% of the patients had elevated cardiac troponin-I, and less than 10% had elevated creatine kinase–MB. Only 11.6% of the patients underwent emergent revascularization; the rate was higher for patients who presented with chest pain or cardiac arrest or shortness of breath than for patients who presented with other symptoms. Conclusions Acute myocardial infarction and the need for emergent revascularization are relatively uncommon among patients who present with nLBBB, especially when symptoms are atypical. Current guidelines for primary percutaneous coronary intervention protocol activation for nLBBB should be reconsidered.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>22575807</pmid><doi>10.1016/j.jelectrocard.2012.04.006</doi><tpages>7</tpages></addata></record>
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subjects Acute myocardial infarction
Aged
Angioplasty, Balloon, Coronary
Bundle-Branch Block - complications
Bundle-Branch Block - diagnosis
Bundle-Branch Block - therapy
Cardiovascular
Creatine Kinase, MB Form - blood
Electrocardiogram
Electrocardiography
Emergencies
Female
Humans
Left bundle branch block
Male
Myocardial Infarction - complications
Myocardial Infarction - diagnosis
Myocardial Infarction - therapy
Primary percutaneous coronary intervention
Troponin I - blood
title Prevalence of acute myocardial infarction in patients with presumably new left bundle-branch block
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