PSEA: Phenotype Set Enrichment Analysis-A New Method for Analysis of Multiple Phenotypes

Most genome‐wide association studies (GWAS) are restricted to one phenotype, even if multiple related or unrelated phenotypes are available. However, an integrated analysis of multiple phenotypes can provide insight into their shared genetic basis and may improve the power of association studies. We...

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Veröffentlicht in:	Genetic epidemiology 2012-04, Vol.36 (3), p.244-252
Hauptverfasser:	Ried, Janina S., Döring, Angela, Oexle, Konrad, Meisinger, Christa, Winkelmann, Juliane, Klopp, Norman, Meitinger, Thomas, Peters, Annette, Suhre, Karsten, Wichmann, H.-Erich, Gieger, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	Blood Proteins - genetics Cohort Studies Erythrocytes - physiology genome-wide association Genome-Wide Association Study - methods Genome-Wide Association Study - statistics & numerical data Genotype Humans Models, Genetic permutation test Phenotype pleiotropy Polymorphism, Single Nucleotide Software
Online-Zugang:	Volltext
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