Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics
Abstract Regional brain volumes were compared between 23 participants with obsessive–compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the...
Gespeichert in:
| Veröffentlicht in: | Psychiatry research. Neuroimaging 2012-04, Vol.202 (1), p.74-76 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 76 |
|---|---|
| container_issue | 1 |
| container_start_page | 74 |
| container_title | Psychiatry research. Neuroimaging |
| container_volume | 202 |
| creator | Exner, Cornelia Zetsche, Ulrike Martin, Vera Rief, Winfried Jansen, Andreas |
| description | Abstract Regional brain volumes were compared between 23 participants with obsessive–compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset. |
| doi_str_mv | 10.1016/j.pscychresns.2011.10.007 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1021451627</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0925492711003519</els_id><sourcerecordid>1021451627</sourcerecordid><originalsourceid>FETCH-LOGICAL-c462t-670b46e6147a45238edad53b490df5a19f25441f0298da3ac59400e7981a85a43</originalsourceid><addsrcrecordid>eNqNks-O0zAQxi0EYsvCK6BwQOKSMnbsJOaAtKr4J62EtMDZcp1J65LEwZOs1BvvwBvyJDhqFxAnTpbt33z-_M0w9ozDmgMvXx7WI7mj20ekgdYCOE_na4DqHlvxuhJ5paC8z1aghcqlFtUFe0R0ABBFXRYP2YUQSisF1Yr5G9z5MNgu20V7zHo7TRgzt7fDDinzQxa2hET-Fn9-_-FCP87dsskaTyE2GF9lN9jZKUnQ3o_ZFDLX-cG7JJhEonVJztPkHT1mD1rbET45r5fsy9s3nzfv8-uP7z5srq5zJ0sx5WUFW1liyWVlpUqGsbGNKrZSQ9Mqy3UrlJS8BaHrxhbWKS0BsNI1t7WysrhkL066YwzfZqTJ9J4cdp0dMMxkOAguFS9FlVB9Ql0MRBFbM0bf23hMkFmSNgfzV9JmSXq5Skmn2qfnZ-Ztj83vyrtoE_D8DFhKcbTRDs7TH66EWnHNE7c5cZhCufUYDTmPg8PGR3STaYL_Lzuv_1G568NXPCIdwhxTk9PvDQkD5tMyGstkcA5QJB_FLzlqueg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1021451627</pqid></control><display><type>article</type><title>Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Exner, Cornelia ; Zetsche, Ulrike ; Martin, Vera ; Rief, Winfried ; Jansen, Andreas</creator><creatorcontrib>Exner, Cornelia ; Zetsche, Ulrike ; Martin, Vera ; Rief, Winfried ; Jansen, Andreas</creatorcontrib><description>Abstract Regional brain volumes were compared between 23 participants with obsessive–compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset.</description><identifier>ISSN: 0925-4927</identifier><identifier>EISSN: 1872-7506</identifier><identifier>DOI: 10.1016/j.pscychresns.2011.10.007</identifier><identifier>PMID: 22595507</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Adult ; Adult and adolescent clinical studies ; Anxiety disorders. Neuroses ; Biological and medical sciences ; Brain - pathology ; Female ; Humans ; Image Processing, Computer-Assisted ; Magnetic Resonance Imaging ; Male ; Medial prefrontal cortex ; Medical sciences ; Middle Aged ; Nerve Fibers, Unmyelinated - pathology ; Neuroimaging ; Obsessive-Compulsive Disorder - pathology ; Obsessive-compulsive disorders ; Obsessive–compulsive disorder ; Organ Size ; Psychiatry ; Psychology. Psychoanalysis. Psychiatry ; Psychopathology. Psychiatry ; Radiology ; Voxel-based morphometry</subject><ispartof>Psychiatry research. Neuroimaging, 2012-04, Vol.202 (1), p.74-76</ispartof><rights>Elsevier Ireland Ltd</rights><rights>2012 Elsevier Ireland Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2012 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c462t-670b46e6147a45238edad53b490df5a19f25441f0298da3ac59400e7981a85a43</citedby><cites>FETCH-LOGICAL-c462t-670b46e6147a45238edad53b490df5a19f25441f0298da3ac59400e7981a85a43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.pscychresns.2011.10.007$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26085191$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22595507$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Exner, Cornelia</creatorcontrib><creatorcontrib>Zetsche, Ulrike</creatorcontrib><creatorcontrib>Martin, Vera</creatorcontrib><creatorcontrib>Rief, Winfried</creatorcontrib><creatorcontrib>Jansen, Andreas</creatorcontrib><title>Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics</title><title>Psychiatry research. Neuroimaging</title><addtitle>Psychiatry Res</addtitle><description>Abstract Regional brain volumes were compared between 23 participants with obsessive–compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset.</description><subject>Adult</subject><subject>Adult and adolescent clinical studies</subject><subject>Anxiety disorders. Neuroses</subject><subject>Biological and medical sciences</subject><subject>Brain - pathology</subject><subject>Female</subject><subject>Humans</subject><subject>Image Processing, Computer-Assisted</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medial prefrontal cortex</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nerve Fibers, Unmyelinated - pathology</subject><subject>Neuroimaging</subject><subject>Obsessive-Compulsive Disorder - pathology</subject><subject>Obsessive-compulsive disorders</subject><subject>Obsessive–compulsive disorder</subject><subject>Organ Size</subject><subject>Psychiatry</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopathology. Psychiatry</subject><subject>Radiology</subject><subject>Voxel-based morphometry</subject><issn>0925-4927</issn><issn>1872-7506</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNks-O0zAQxi0EYsvCK6BwQOKSMnbsJOaAtKr4J62EtMDZcp1J65LEwZOs1BvvwBvyJDhqFxAnTpbt33z-_M0w9ozDmgMvXx7WI7mj20ekgdYCOE_na4DqHlvxuhJ5paC8z1aghcqlFtUFe0R0ABBFXRYP2YUQSisF1Yr5G9z5MNgu20V7zHo7TRgzt7fDDinzQxa2hET-Fn9-_-FCP87dsskaTyE2GF9lN9jZKUnQ3o_ZFDLX-cG7JJhEonVJztPkHT1mD1rbET45r5fsy9s3nzfv8-uP7z5srq5zJ0sx5WUFW1liyWVlpUqGsbGNKrZSQ9Mqy3UrlJS8BaHrxhbWKS0BsNI1t7WysrhkL066YwzfZqTJ9J4cdp0dMMxkOAguFS9FlVB9Ql0MRBFbM0bf23hMkFmSNgfzV9JmSXq5Skmn2qfnZ-Ztj83vyrtoE_D8DFhKcbTRDs7TH66EWnHNE7c5cZhCufUYDTmPg8PGR3STaYL_Lzuv_1G568NXPCIdwhxTk9PvDQkD5tMyGstkcA5QJB_FLzlqueg</recordid><startdate>20120430</startdate><enddate>20120430</enddate><creator>Exner, Cornelia</creator><creator>Zetsche, Ulrike</creator><creator>Martin, Vera</creator><creator>Rief, Winfried</creator><creator>Jansen, Andreas</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20120430</creationdate><title>Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics</title><author>Exner, Cornelia ; Zetsche, Ulrike ; Martin, Vera ; Rief, Winfried ; Jansen, Andreas</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c462t-670b46e6147a45238edad53b490df5a19f25441f0298da3ac59400e7981a85a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Adult</topic><topic>Adult and adolescent clinical studies</topic><topic>Anxiety disorders. Neuroses</topic><topic>Biological and medical sciences</topic><topic>Brain - pathology</topic><topic>Female</topic><topic>Humans</topic><topic>Image Processing, Computer-Assisted</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medial prefrontal cortex</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nerve Fibers, Unmyelinated - pathology</topic><topic>Neuroimaging</topic><topic>Obsessive-Compulsive Disorder - pathology</topic><topic>Obsessive-compulsive disorders</topic><topic>Obsessive–compulsive disorder</topic><topic>Organ Size</topic><topic>Psychiatry</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopathology. Psychiatry</topic><topic>Radiology</topic><topic>Voxel-based morphometry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Exner, Cornelia</creatorcontrib><creatorcontrib>Zetsche, Ulrike</creatorcontrib><creatorcontrib>Martin, Vera</creatorcontrib><creatorcontrib>Rief, Winfried</creatorcontrib><creatorcontrib>Jansen, Andreas</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Psychiatry research. Neuroimaging</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Exner, Cornelia</au><au>Zetsche, Ulrike</au><au>Martin, Vera</au><au>Rief, Winfried</au><au>Jansen, Andreas</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics</atitle><jtitle>Psychiatry research. Neuroimaging</jtitle><addtitle>Psychiatry Res</addtitle><date>2012-04-30</date><risdate>2012</risdate><volume>202</volume><issue>1</issue><spage>74</spage><epage>76</epage><pages>74-76</pages><issn>0925-4927</issn><eissn>1872-7506</eissn><abstract>Abstract Regional brain volumes were compared between 23 participants with obsessive–compulsive disorder (OCD) and 36 healthy controls using magnetic resonance imaging with voxel-based morphometry. A volumetric decrease in OCD was found in the right mediofrontal cortex. An increase was found in the left temporoparietal cortex. Volume alterations were related to symptom severity and age of onset.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>22595507</pmid><doi>10.1016/j.pscychresns.2011.10.007</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0925-4927 |
| ispartof | Psychiatry research. Neuroimaging, 2012-04, Vol.202 (1), p.74-76 |
| issn | 0925-4927 1872-7506 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1021451627 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adult Adult and adolescent clinical studies Anxiety disorders. Neuroses Biological and medical sciences Brain - pathology Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Male Medial prefrontal cortex Medical sciences Middle Aged Nerve Fibers, Unmyelinated - pathology Neuroimaging Obsessive-Compulsive Disorder - pathology Obsessive-compulsive disorders Obsessive–compulsive disorder Organ Size Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Radiology Voxel-based morphometry |
| title | Regional gray matter changes in obsessive–compulsive disorder: Relationship to clinical characteristics |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-18T08%3A44%3A37IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Regional%20gray%20matter%20changes%20in%20obsessive%E2%80%93compulsive%20disorder:%20Relationship%20to%20clinical%20characteristics&rft.jtitle=Psychiatry%20research.%20Neuroimaging&rft.au=Exner,%20Cornelia&rft.date=2012-04-30&rft.volume=202&rft.issue=1&rft.spage=74&rft.epage=76&rft.pages=74-76&rft.issn=0925-4927&rft.eissn=1872-7506&rft_id=info:doi/10.1016/j.pscychresns.2011.10.007&rft_dat=%3Cproquest_cross%3E1021451627%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1021451627&rft_id=info:pmid/22595507&rft_els_id=S0925492711003519&rfr_iscdi=true |