Killing me softly – Suicidal erythrocyte death

Similar to nucleated cells, erythrocytes may undergo suicidal death or eryptosis, which is characterized by cell shrinkage, cell membrane blebbing and cell membrane phospholipid scrambling. Eryptotic cells are removed and thus prevented from undergoing hemolysis. Eryptosis is stimulated by Ca2+ foll...

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Veröffentlicht in:	The international journal of biochemistry & cell biology 2012-08, Vol.44 (8), p.1236-1243
Hauptverfasser:	Lang, Elisabeth, Qadri, Syed M., Lang, Florian
Format:	Artikel
Sprache:	eng
Schlagworte:	AMP-activated protein kinase Anemia animal models Animals Apoptosis Apoptosis - physiology calcium Calcium - metabolism Calcium - pharmacology catecholamines cell death cell membranes ceramides Ceramides - pharmacology cGMP-dependent protein kinase diabetes endothelial cells energy Eryptosis erythrocytes Erythrocytes - physiology erythropoiesis erythropoietin fever glucose 6-phosphate glucose-6-phosphate 1-dehydrogenase hemoglobinuria hemolysis hepatolenticular degeneration Humans iron Malaria Mice Models, Biological nitric oxide non-specific protein-tyrosine kinase nutrient deficiencies oxidative stress phosphates phospholipids platelet-activating factor Red blood cell renal failure Sepsis sepsis (infection) shrinkage sickle cell anemia Signal Transduction - drug effects Signal Transduction - physiology taurine thalassemia xenobiotics Xenobiotics - pharmacology
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