MicroRNA-126 contributes to renal microvascular heterogeneity of VCAM-1 protein expression in acute inflammation

Endothelial cells in different microvascular segments of the kidney have diverse functions and exhibit differential responsiveness to disease stimuli. The responsible molecular mechanisms are largely unknown. We previously showed that during hemorrhagic shock, VCAM-1 protein was expressed primarily...

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Veröffentlicht in:	American journal of physiology. Renal physiology 2012-06, Vol.302 (12), p.F1630-F1639
Hauptverfasser:	Asgeirsdóttir, S A, van Solingen, C, Kurniati, N F, Zwiers, P J, Heeringa, P, van Meurs, M, Satchell, S C, Saleem, M A, Mathieson, P W, Banas, B, Kamps, J A A M, Rabelink, T J, van Zonneveld, A J, Molema, G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cells, Cultured Disease Models, Animal E-Selectin - genetics E-Selectin - metabolism Endothelial Cells - metabolism Endothelium, Vascular - cytology Endothelium, Vascular - metabolism Gene expression Glomerulonephritis - genetics Glomerulonephritis - metabolism Humans Inflammation - genetics Inflammation - metabolism Kidney - metabolism Kidney diseases Kidney Glomerulus - metabolism Mice MicroRNAs - genetics MicroRNAs - metabolism Molecular structure Physiology Proteins Ribonucleic acid RNA Tumor Necrosis Factor-alpha - pharmacology Vascular Cell Adhesion Molecule-1 - genetics Vascular Cell Adhesion Molecule-1 - metabolism
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