The biological behavior of SDF-1/CXCR4 in patients with myelodysplastic syndrome

The purpose of this investigation is to evaluate the biological behavior of stromal cell-derived factor-l (SDF-1) in migration, adhesion, and apoptosis as well as the related signaling transduction pathways in patients with myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). We chose 22...

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Veröffentlicht in:	Medical oncology (Northwood, London, England) London, England), 2012-06, Vol.29 (2), p.1202-1208
Hauptverfasser:	Yang, Rui, Pu, Jie, Guo, Juan, Xu, Feng, Zhang, Zheng, Zhao, Youshan, Zhang, Xi, Gu, ShuCheng, Chang, ChunKang, Li, Xiao
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase Acute myeloid leukemia Apoptosis Bone Marrow - metabolism Bone Marrow - pathology Case-Control Studies CD34 antigen Cell Adhesion Cell migration Cell Movement Chemokine CXCL12 - metabolism CXCR4 protein Enzyme-Linked Immunosorbent Assay Flow Cytometry Hematology Humans Internal Medicine Medicine Medicine & Public Health Myelodysplastic syndrome Myelodysplastic Syndromes - metabolism Myelodysplastic Syndromes - pathology Neoplasm Grading Oncology Original Paper Pathology Phosphatidylinositol 3-Kinases - metabolism phosphatidylserine Receptors, CXCR4 - metabolism SDF-1 protein Signal Transduction Sincalide - metabolism Stromal Cells - metabolism Stromal Cells - pathology Tumor Cells, Cultured Wortmannin
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