A single amino acid substitution controls DAF-dependent phenotype of echovirus 11 in rhabdomyosarcoma cells

► A single amino acid substitution controls the usage of DAF receptor by echovirus 11. ► Antibody to beta2-microglobulin inhibits echovirus 11 daf+ and daf− clones. ► Daf+ variants of echovirus 11 are positively selected in the RD cell line. Decay accelerating factor (DAF, CD55) is used by DAF-depen...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Virus research 2012-06, Vol.166 (1-2), p.87-96
Hauptverfasser:	Novoselov, Alexey V., Rezaykin, Alexey V., Sergeev, Alexander G., Fadeyev, Fedor A., Grigoryeva, Julia V., Sokolova, Zoya I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution beta 2-microglobulin Beta2-microglobulin binding sites Capsid protein Capsid Proteins - genetics Capsid Proteins - metabolism CD55 CD55 Antigens - metabolism Cell Line, Tumor clones coat proteins DAF decay-accelerating factor Echovirus Echovirus 11 Enterovirus B, Human - genetics Enterovirus B, Human - physiology Histocompatibility antigen HLA HLA antigens Humans Infection Molecular Sequence Data Monoclonal antibodies Mutant Proteins - genetics Mutant Proteins - metabolism phenotype physiological transport Receptor receptors Receptors, Virus - metabolism Rhabdomyosarcoma Sequence Analysis, DNA Structural proteins Uncoating Virus Internalization
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!