$The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures$

The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures

Abstract Background An elevated level of plasma homocysteine (Hcy) is a known risk factor for osteoporotic fractures. In addition, Hcy is related to DNA-methylation metabolism. To determine whether the association between Hcy and fractures is explained by an altered methylation capacity, we investig...

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Veröffentlicht in:	Bone (New York, N.Y.) N.Y.), 2012-06, Vol.50 (6), p.1401-1405
Hauptverfasser:	Enneman, A.W, van der Velde, N, de Jonge, R, Heil, S.G, Stolk, L, Hofman, A, Rivadeneira, F, Zillikens, M.C, Uitterlinden, A.G, van Meurs, J.B.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Biological and medical sciences Bone Density Bone mineral density Diseases of the osteoarticular system DNA methylation Dual energy X-ray absorptiometry Female Fractures Fundamental and applied biological sciences. Psychology Hip Homocysteine Homocysteine - blood Humans Incidence Injuries of the limb. Injuries of the spine Linear Models Medical sciences Metabolism Metabolites Methylation Middle Aged Netherlands - epidemiology Orthopedics Osteoporosis Osteoporosis. Osteomalacia. Paget disease Osteoporotic Fractures - blood Osteoporotic Fractures - epidemiology Osteoporotic Fractures - etiology Proportional Hazards Models Risk assessment Risk Factors S-adenosylhomocysteine S-Adenosylhomocysteine - blood S-Adenosylmethionine S-Adenosylmethionine - blood Traumas. Diseases due to physical agents Vertebrates: anatomy and physiology, studies on body, several organs or systems
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