Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype?
Background Previous studies demonstrated clinical differences of early- and late-onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied. Objective Assessment of epidemiology and clinical features of psoriasis...
Gespeichert in:
| Veröffentlicht in: | International journal of dermatology 2012-01, Vol.51 (1), p.53-58 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 58 |
|---|---|
| container_issue | 1 |
| container_start_page | 53 |
| container_title | International journal of dermatology |
| container_volume | 51 |
| creator | Kwon, Hyuck Hoon Kwon, In Ho Youn, Jai Il |
| description | Background Previous studies demonstrated clinical differences of early- and late-onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied. Objective Assessment of epidemiology and clinical features of psoriasis first occurring over the age of 60years, so-called elderly-onset psoriasis, based on clinical data. Materials and methods Among 4049 patients visiting our psoriasis clinic for the last 27years, patients were first divided into early- (onset age before 30years) and late-onset psoriasis (onset age after 30years) based on our previous studies. Then, patients of late-onset psoriasis were further divided into middle age-onset group (onset age between 30 and 60years) and elderly-onset group (onset age over 60years). Clinical characteristics of elderly-onset psoriasis were compared with early- and middle age-onset groups. We acquired the data both by physician's assessments and patients' responses. Results Elderly-onset patients comprised 3.2% of total patients, 129 out of 4049. They have shown a lower incidence of family history (P |
| doi_str_mv | 10.1111/j.1365-4632.2011.04979.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1020836168</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1020836168</sourcerecordid><originalsourceid>FETCH-LOGICAL-p103t-39e546d9f8220a1e86cfd248d90c6bc78498325a8f32b6ebed00b7da3abc5d773</originalsourceid><addsrcrecordid>eNpNjE1LxDAYhIMoWFf_Q45eWvPRpokXkcUvWPCi5yVN3q5Zsk1NUrH_3ooizmUYnplBCFNS0UVX-4py0ZS14KxihNKK1KpV1ecRKv7AMSrIgkpFGnWKzlLaL5EzWhfosPZucEZ7nPJkZxx6PKYQnU4u4WDMFKMbdjh8QMT5DbDewXdHkBl0TNd4aYG3EP1chiFB_rfW2LqU3WAyTlOX5xFuztFJr32Ci19fodf7u5f1Y7l5fnha327KkRKeS66gqYVVvWSMaApSmN6yWlpFjOhMK2slOWu07DnrBHRgCelaq7nuTGPblq_Q5c_vGMP7BClvDy4Z8F4PEKa0pYQRyQUVkn8BKNtgEw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1020836168</pqid></control><display><type>article</type><title>Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype?</title><source>Wiley Online Library Journals Frontfile Complete</source><creator>Kwon, Hyuck Hoon ; Kwon, In Ho ; Youn, Jai Il</creator><creatorcontrib>Kwon, Hyuck Hoon ; Kwon, In Ho ; Youn, Jai Il</creatorcontrib><description><![CDATA[Background Previous studies demonstrated clinical differences of early- and late-onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied. Objective Assessment of epidemiology and clinical features of psoriasis first occurring over the age of 60years, so-called elderly-onset psoriasis, based on clinical data. Materials and methods Among 4049 patients visiting our psoriasis clinic for the last 27years, patients were first divided into early- (onset age before 30years) and late-onset psoriasis (onset age after 30years) based on our previous studies. Then, patients of late-onset psoriasis were further divided into middle age-onset group (onset age between 30 and 60years) and elderly-onset group (onset age over 60years). Clinical characteristics of elderly-onset psoriasis were compared with early- and middle age-onset groups. We acquired the data both by physician's assessments and patients' responses. Results Elderly-onset patients comprised 3.2% of total patients, 129 out of 4049. They have shown a lower incidence of family history (P<0.05). The severity assessed by PASI score, body surface extent, and activity of individual lesions demonstrated that psoriasis of the elderly-onset group was generally milder compared with early- and middle age-onset groups (P<0.05). In clinical phenotypes, the proportion of guttate type and generalized pustular psoriasis type decreased remarkably, while that of erythroderma type increased (P<0.05). There was a significant change in the body part of origin comparing early- and middle age-onset groups (P<0.05). The proportion of scalp increased, while that of knee-elbow and trunk decreased significantly (P<0.05). Patients' subjective sensation of disease course improved statistically comparing early- and middle age-onset groups (P<0.05). There was no significant change in the degree of pruritus on psoriatic lesions and nail involvement (P>0.05). Conclusion The elderly-onset group demonstrated milder disease courses and some changes in clinical phenotypes and body part of origin compared with early- and middle age-onset groups. Therefore, it seems that patients whose onset of psoriasis was over the age of 60years might have distinct clinical features in some clinical aspects.]]></description><identifier>ISSN: 0011-9059</identifier><identifier>EISSN: 1365-4632</identifier><identifier>DOI: 10.1111/j.1365-4632.2011.04979.x</identifier><language>eng</language><subject>Age ; Clinical aspects ; Data processing ; Epidemiology ; Genetics ; Geriatrics ; Lesions ; pruritus ; Psoriasis ; Scalp</subject><ispartof>International journal of dermatology, 2012-01, Vol.51 (1), p.53-58</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Kwon, Hyuck Hoon</creatorcontrib><creatorcontrib>Kwon, In Ho</creatorcontrib><creatorcontrib>Youn, Jai Il</creatorcontrib><title>Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype?</title><title>International journal of dermatology</title><description><![CDATA[Background Previous studies demonstrated clinical differences of early- and late-onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied. Objective Assessment of epidemiology and clinical features of psoriasis first occurring over the age of 60years, so-called elderly-onset psoriasis, based on clinical data. Materials and methods Among 4049 patients visiting our psoriasis clinic for the last 27years, patients were first divided into early- (onset age before 30years) and late-onset psoriasis (onset age after 30years) based on our previous studies. Then, patients of late-onset psoriasis were further divided into middle age-onset group (onset age between 30 and 60years) and elderly-onset group (onset age over 60years). Clinical characteristics of elderly-onset psoriasis were compared with early- and middle age-onset groups. We acquired the data both by physician's assessments and patients' responses. Results Elderly-onset patients comprised 3.2% of total patients, 129 out of 4049. They have shown a lower incidence of family history (P<0.05). The severity assessed by PASI score, body surface extent, and activity of individual lesions demonstrated that psoriasis of the elderly-onset group was generally milder compared with early- and middle age-onset groups (P<0.05). In clinical phenotypes, the proportion of guttate type and generalized pustular psoriasis type decreased remarkably, while that of erythroderma type increased (P<0.05). There was a significant change in the body part of origin comparing early- and middle age-onset groups (P<0.05). The proportion of scalp increased, while that of knee-elbow and trunk decreased significantly (P<0.05). Patients' subjective sensation of disease course improved statistically comparing early- and middle age-onset groups (P<0.05). There was no significant change in the degree of pruritus on psoriatic lesions and nail involvement (P>0.05). Conclusion The elderly-onset group demonstrated milder disease courses and some changes in clinical phenotypes and body part of origin compared with early- and middle age-onset groups. Therefore, it seems that patients whose onset of psoriasis was over the age of 60years might have distinct clinical features in some clinical aspects.]]></description><subject>Age</subject><subject>Clinical aspects</subject><subject>Data processing</subject><subject>Epidemiology</subject><subject>Genetics</subject><subject>Geriatrics</subject><subject>Lesions</subject><subject>pruritus</subject><subject>Psoriasis</subject><subject>Scalp</subject><issn>0011-9059</issn><issn>1365-4632</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><recordid>eNpNjE1LxDAYhIMoWFf_Q45eWvPRpokXkcUvWPCi5yVN3q5Zsk1NUrH_3ooizmUYnplBCFNS0UVX-4py0ZS14KxihNKK1KpV1ecRKv7AMSrIgkpFGnWKzlLaL5EzWhfosPZucEZ7nPJkZxx6PKYQnU4u4WDMFKMbdjh8QMT5DbDewXdHkBl0TNd4aYG3EP1chiFB_rfW2LqU3WAyTlOX5xFuztFJr32Ci19fodf7u5f1Y7l5fnha327KkRKeS66gqYVVvWSMaApSmN6yWlpFjOhMK2slOWu07DnrBHRgCelaq7nuTGPblq_Q5c_vGMP7BClvDy4Z8F4PEKa0pYQRyQUVkn8BKNtgEw</recordid><startdate>20120101</startdate><enddate>20120101</enddate><creator>Kwon, Hyuck Hoon</creator><creator>Kwon, In Ho</creator><creator>Youn, Jai Il</creator><scope>7T2</scope><scope>7T5</scope><scope>7U2</scope><scope>C1K</scope><scope>H94</scope></search><sort><creationdate>20120101</creationdate><title>Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype?</title><author>Kwon, Hyuck Hoon ; Kwon, In Ho ; Youn, Jai Il</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p103t-39e546d9f8220a1e86cfd248d90c6bc78498325a8f32b6ebed00b7da3abc5d773</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Age</topic><topic>Clinical aspects</topic><topic>Data processing</topic><topic>Epidemiology</topic><topic>Genetics</topic><topic>Geriatrics</topic><topic>Lesions</topic><topic>pruritus</topic><topic>Psoriasis</topic><topic>Scalp</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kwon, Hyuck Hoon</creatorcontrib><creatorcontrib>Kwon, In Ho</creatorcontrib><creatorcontrib>Youn, Jai Il</creatorcontrib><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Safety Science and Risk</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><jtitle>International journal of dermatology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kwon, Hyuck Hoon</au><au>Kwon, In Ho</au><au>Youn, Jai Il</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype?</atitle><jtitle>International journal of dermatology</jtitle><date>2012-01-01</date><risdate>2012</risdate><volume>51</volume><issue>1</issue><spage>53</spage><epage>58</epage><pages>53-58</pages><issn>0011-9059</issn><eissn>1365-4632</eissn><abstract><![CDATA[Background Previous studies demonstrated clinical differences of early- and late-onset psoriasis. However, epidemiological data and clinical characteristics of psoriasis occurring in geriatric patients have been rarely studied. Objective Assessment of epidemiology and clinical features of psoriasis first occurring over the age of 60years, so-called elderly-onset psoriasis, based on clinical data. Materials and methods Among 4049 patients visiting our psoriasis clinic for the last 27years, patients were first divided into early- (onset age before 30years) and late-onset psoriasis (onset age after 30years) based on our previous studies. Then, patients of late-onset psoriasis were further divided into middle age-onset group (onset age between 30 and 60years) and elderly-onset group (onset age over 60years). Clinical characteristics of elderly-onset psoriasis were compared with early- and middle age-onset groups. We acquired the data both by physician's assessments and patients' responses. Results Elderly-onset patients comprised 3.2% of total patients, 129 out of 4049. They have shown a lower incidence of family history (P<0.05). The severity assessed by PASI score, body surface extent, and activity of individual lesions demonstrated that psoriasis of the elderly-onset group was generally milder compared with early- and middle age-onset groups (P<0.05). In clinical phenotypes, the proportion of guttate type and generalized pustular psoriasis type decreased remarkably, while that of erythroderma type increased (P<0.05). There was a significant change in the body part of origin comparing early- and middle age-onset groups (P<0.05). The proportion of scalp increased, while that of knee-elbow and trunk decreased significantly (P<0.05). Patients' subjective sensation of disease course improved statistically comparing early- and middle age-onset groups (P<0.05). There was no significant change in the degree of pruritus on psoriatic lesions and nail involvement (P>0.05). Conclusion The elderly-onset group demonstrated milder disease courses and some changes in clinical phenotypes and body part of origin compared with early- and middle age-onset groups. Therefore, it seems that patients whose onset of psoriasis was over the age of 60years might have distinct clinical features in some clinical aspects.]]></abstract><doi>10.1111/j.1365-4632.2011.04979.x</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0011-9059 |
| ispartof | International journal of dermatology, 2012-01, Vol.51 (1), p.53-58 |
| issn | 0011-9059 1365-4632 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1020836168 |
| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Age Clinical aspects Data processing Epidemiology Genetics Geriatrics Lesions pruritus Psoriasis Scalp |
| title | Clinical study of psoriasis occurring over the age of 60years: is elderly-onset psoriasis a distinct subtype? |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T20%3A36%3A18IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Clinical%20study%20of%20psoriasis%20occurring%20over%20the%20age%20of%2060years:%20is%20elderly-onset%20psoriasis%20a%20distinct%20subtype?&rft.jtitle=International%20journal%20of%20dermatology&rft.au=Kwon,%20Hyuck%20Hoon&rft.date=2012-01-01&rft.volume=51&rft.issue=1&rft.spage=53&rft.epage=58&rft.pages=53-58&rft.issn=0011-9059&rft.eissn=1365-4632&rft_id=info:doi/10.1111/j.1365-4632.2011.04979.x&rft_dat=%3Cproquest%3E1020836168%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1020836168&rft_id=info:pmid/&rfr_iscdi=true |