The expression of TLR pathway molecules in peripheral blood mononuclear cells and their relationship with tumor invasion and cytokine secretion in laryngeal carcinoma

The aim of this study was to analyze of TLRs mRNA expression in peripheral blood mononuclear cells as potential biomarkers of neoplastic lesions progress and to evaluate their role in the possible mechanisms responsible for the secretion of cytokines in laryngeal cancer. The analysis of TLR2, TLR4,...

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Veröffentlicht in:	Advances in medical sciences 2012-06, Vol.57 (1), p.124-135
Hauptverfasser:	Starska, K, Forma, E, Bryś, M, Głowacka, E, Lewy-Trenda, I, Łukomski, M, Krajewska, WM
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Enzyme-Linked Immunosorbent Assay Female Humans Interleukin-6 - metabolism Interleukin-8 - metabolism laryngeal carcinoma Laryngeal Neoplasms - metabolism Leukocytes, Mononuclear - metabolism Male Middle Aged proinflammatory cytokines Reverse Transcriptase Polymerase Chain Reaction TNF Receptor-Associated Factor 6 - genetics TNF Receptor-Associated Factor 6 - metabolism toll-like receptor (TLR) pathway molecules Toll-Like Receptor 2 - genetics Toll-Like Receptor 2 - metabolism Toll-Like Receptor 4 - genetics Toll-Like Receptor 4 - metabolism Toll-Like Receptors - genetics Toll-Like Receptors - metabolism tumor front grading (TFG) Tumor Necrosis Factor-alpha - metabolism
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