The cytochrome P-450 2C9/2C19 but not the ABCB1 genetic polymorphism may be associated with the liver cytochrome 3A4 induction by phenytoin

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Veröffentlicht in:	Journal of clinical psychopharmacology 2012-06, Vol.32 (3), p.429-431
Hauptverfasser:	Chhun, Stéphanie, Verstuyft, Céline, Rizzo-Padoin, Nathalie, Simoneau, Guy, Becquemont, Laurent, Bergmann, Jean François, Mouly, Stéphane
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Anticonvulsants - blood Anticonvulsants - pharmacokinetics Anticonvulsants - pharmacology Aryl Hydrocarbon Hydroxylases - genetics Aryl Hydrocarbon Hydroxylases - metabolism ATP Binding Cassette Transporter, Subfamily B ATP Binding Cassette Transporter, Subfamily B, Member 1 - genetics ATP Binding Cassette Transporter, Subfamily B, Member 1 - metabolism Breath Tests Cytochrome P-450 CYP2C19 Cytochrome P-450 CYP2C9 Cytochrome P-450 CYP3A - biosynthesis Enzyme Induction - drug effects Erythromycin - analogs & derivatives Erythromycin - analysis Erythromycin - pharmacokinetics France Gene Frequency Humans Liver - drug effects Liver - enzymology Male Middle Aged Phenytoin - blood Phenytoin - pharmacokinetics Phenytoin - pharmacology Polymorphism, Genetic Radioactive Tracers Young Adult
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