Pericyte-Coverage of Human Tumor Vasculature and Nanoparticle Permeability

Nano drug delivery systems (nanoDDS) are a promising strategy for treatment of human tumors. As indicated by our previous work, the extent of pericyte-coverage of tumor vasculature is important to determining nanoDDS efficacy since intratumoral accumulation of nanoDDS is less in tumor models with pe...

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Veröffentlicht in:Biological & pharmaceutical bulletin 2012/05/01, Vol.35(5), pp.761-766
Hauptverfasser: Zhang, Liuzhe, Nishihara, Hiroshi, Kano, Mitsunobu R
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Sprache:eng
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