High White Blood Cell Concentration in the Peripheral Blood Stem Cell Product Can Induce Seizures during Infusion of Autologous Peripheral Blood Stem Cells

Seizures as a complication of the infusion of autologous peripheral blood stem cells (PBSC) are rare. Seizures during infusion of autologous PBSC in 3 of our patients prompted us to review our cell therapy and cytapheresis protocols and procedures. We retrospectively analyzed 159 adult patients coll...

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Veröffentlicht in:	Biology of blood and marrow transplantation 2012-07, Vol.18 (7), p.1055-1060
Hauptverfasser:	Bachier, Carlos, Potter, Josh, Potter, Grant, Sugay, Rominna, Shaughnessy, Paul, Chan, Kawah, Jude, Veronica, Madden, Renee, LeMaistre, Charles F
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Apheresis Autologous transplant Cell concentration Cryopreservation Female Granulocyte Colony-Stimulating Factor - administration & dosage Hematology, Oncology and Palliative Medicine Hematopoietic Stem Cell Mobilization - methods Hematopoietic Stem Cell Transplantation - adverse effects Heterocyclic Compounds - administration & dosage Humans Leukapheresis Leukocyte Count Male Middle Aged Retrospective Studies Seizure Seizures - etiology Seizures - prevention & control Specimen Handling - methods Transplantation, Autologous
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