Complete morphologic and molecular remission after introduction of dasatinib in the treatment of a pediatric patient with t-cell acute lymphoblastic leukemia and ABL1 amplification
T‐cell acute lymphoblastic leukemia (ALL) accounts for 15% of ALL cases in children and has been associated with a worse prognosis. Cytogenetic studies show an abnormal karyotype in 50–60% of the T‐cell ALL patients; ABL1 fusions are present in approximately 8% of the cases. Dasatinib, a second‐gene...
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Veröffentlicht in: | Pediatric blood & cancer 2012-08, Vol.59 (2), p.333-334 |
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