Murine models in mantle cell lymphoma

Mantle cell lymphoma (MCL), an aggressive, heterogeneous B-cell lymphoma associated with a relatively short survival has been challenging to study in the laboratory due to the lack of in vitro and in vivo models that accurately recapitulate the disease. Advancement has been made in the characterizat...

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Veröffentlicht in:	Best practice & research. Clinical haematology 2012-06, Vol.25 (2), p.153-163
Hauptverfasser:	Zullo, Kelly, B.S, Amengual, Jennifer E., M.D, O'Connor, Owen A., M.D., Ph.D, Scotto, Luigi, Ph.D
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents - administration & dosage Antineoplastic Agents - therapeutic use Biological Specimen Banks cell bank Cell Line, Tumor - drug effects Cell Line, Tumor - metabolism Cell Line, Tumor - pathology cell lines Disease Models, Animal Genes, Reporter Hematology, Oncology and Palliative Medicine Humans Luciferases Lymphoma, Mantle-Cell - drug therapy Lymphoma, Mantle-Cell - genetics mantle cell lymphoma Mice Mice, Transgenic Molecular Imaging transgenic mouse models Tumor Burden - drug effects Xenograft Model Antitumor Assays xenograft mouse models
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