Recent advances on the role of tumor exosomes in immunosuppression and disease progression

Abstract Exosomes are endosomal-derived nanovesicles released by most cells types, including tumor cells, and principally involved in intercellular communication in physiology and disease. Tumor exosomes are gaining increasing interest in medicine and oncology as efficient tools for the delivery of...

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Veröffentlicht in:	Seminars in cancer biology 2012-08, Vol.22 (4), p.342-349
Hauptverfasser:	Filipazzi, Paola, Bürdek, Maja, Villa, Antonello, Rivoltini, Licia, Huber, Veronica
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cancer treatment Disease Progression Drug Resistance, Neoplasm Exosomes - metabolism Hematology, Oncology and Palliative Medicine Humans Immune Tolerance Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Microvesicles Myeloid Cells - immunology Myeloid Cells - metabolism Myeloid-derived suppressor cells Neoplasms - immunology Neoplasms - metabolism Neoplasms - pathology NK dysfunction T cell apoptosis T-Lymphocytes - immunology T-Lymphocytes - metabolism Tumor Microenvironment
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