Characterization of PEGylated nanoliposomes co-remotely loaded with topotecan and vincristine: relating structure and pharmacokinetics to therapeutic efficacy

Recently, developing drug delivery systems exhibiting controlled drug release at the tumor sites emerged as an attractive option for enhancing anticancer therapeutic efficacy. It seems, however, unlikely that single agent therapies will prove effective enough against the myriad cells present within...

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Veröffentlicht in:Journal of controlled release 2012-06, Vol.160 (2), p.281-289
Hauptverfasser: Zucker, Daniel, Andriyanov, Alexander V., Steiner, Ariel, Raviv, Uri, Barenholz, Yechezkel
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Sprache:eng
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